Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | AGER | Q15109 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | IKBKB | O14920 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.41 |
| ▸ | WNT3A | P56704 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30131336 | 1.00 | SMN1; SMN2 (0.49) | SMN1; SMN2RAB9AALDH1A1KDM4ECYP3A4 | |
| Formic Acid SCHEMBL2589657 | 0.93 | SMN1; SMN2 (0.44) | SMN1; SMN2RAB9AALDH1A1KDM4ECYP3A4 | |
| SCHEMBL29535774 | 0.81 | KDM4E (0.61) | SMN1; SMN2RAB9AALDH1A1KDM4ECYP3A4 | |
| SCHEMBL209954 | 0.81 | KDM4E (0.61) | SMN1; SMN2RAB9AALDH1A1KDM4ECYP3A4 | |
| SCHEMBL29229156 | 0.81 | KDM4E (0.45) | SMN1; SMN2RAB9AALDH1A1KDM4ECYP3A4 | |
| SCHEMBL3412671 | 0.81 | ALDH1A1 (0.46) | SMN1; SMN2RAB9AALDH1A1KDM4ECYP3A4 | |
| SCHEMBL30644588 | 0.81 | ALDH1A1 (0.42) | SMN1; SMN2RAB9AALDH1A1KDM4ECYP3A4 | |
| SCHEMBL365395 | 0.79 | ALDH1A1 (0.45) | SMN1; SMN2RAB9AALDH1A1KDM4ECYP3A4 | |
| SCHEMBL29229354 | 0.79 | ALDH1A1 (0.44) | SMN1; SMN2RAB9AALDH1A1KDM4ECYP3A4 | |
| Hydrochloric Acid SCHEMBL5277146 | 0.79 | KDM4E (0.59) | SMN1; SMN2RAB9AALDH1A1KDM4ECYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 98 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110195238-A | A kind of method that the electrochemistry dechlorination of trichloromethyl pyridine derivative prepares amide | 浙江工业大学 | 2019-09-03 | — | — | CN | claimed |
| CN-106008355-B | Compound and its purposes as BACE inhibitor | 阿斯利康(瑞典)有限公司 | 2019-05-03 | — | — | CN | claimed |
| CN-108610284-A | A kind of preparation method of Rui Gefeini derivatives | 梯尔希（南京）药物研发有限公司 | 2018-10-02 | — | — | CN | claimed |
| CN-104177292-A | Method for industrial production of sorafenib tosylate polymorphic form I | YITENG PHARMACEUTICAL TAIZHOU CO LTD | 2014-12-03 | — | — | CN | claimed |
| US-20110312935-A1 | 1H-Benz Imidazole-5-Carboxamides As Anti-Inflammatory Agents | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-12-22 | — | — | US | claimed |
| EP-4605089-A1 | COMPOUNDS USEFUL IN MODULATING EGFR AND PI3K | Mekanistic Therapeutics LLC (US) | 2025-08-27 | — | — | EP | disclosed |
| WO-2024086296-A1 | COMPOUNDS USEFUL IN MODULATING EGFR AND PI3K | MEKANISTIC THERAPEUTICS LLC (US) | 2024-04-25 | — | — | WO | disclosed |
| CN-114163382-B | Cyclobutanamide compound or salts and composition acceptable by pesticides and application thereof | 海利尔药业集团股份有限公司 | 2024-02-27 | — | — | CN | disclosed |
| WO-2023216237-A1 | HETEROCYCLIC COMPOUNDS AS KINASE INHIBITORS, COMPOSITIONS, AND METHODS OF USE THEREOF | JS INNOMED HOLDINGS LTD. (KY) | 2023-11-16 | — | — | WO | disclosed |
| CN-115974774-A | Preparation method and application of chloropyridine formic acid | 利尔化学股份有限公司 | 2023-04-18 | — | — | CN | disclosed |
| WO-2023282702-A1 | SHP2 INHIBITOR AND USE THEREOF | 주식회사 카나프테라퓨틱스 | 2023-01-12 | — | — | WO | disclosed |
| CN-114163382-A | Cyclobutanamide compound or salt thereof acceptable as pesticide, composition and application thereof | 海利尔药业集团股份有限公司 | 2022-03-11 | — | — | CN | disclosed |
| WO-2009043747-A2 | N-HETEROCYCLIC BIARYL CARBOXAMIDES AS CCR RECEPTOR ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2009-04-09 | — | — | WO | disclosed |
| US-20090048238-A1 | NOVEL BIARYL DERIVATIVES | HOFFMANN-LA ROCHE, INC. | 2009-02-19 | — | — | US | disclosed |
| WO-2007035428-A1 | MET KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-03-29 | — | — | WO | disclosed |
| EP-1764360-A1 | UREA DERIVATIVE | Sankyo Company, Limited (JP) | 2007-03-21 | — | — | EP | disclosed |
| EP-1115707-B1 | BENZAMIDE DERIVATIVES AND THER USE AS CYTOKINE INHIBITORS | ASTRAZENECA AB (SE) | 2003-11-12 | — | — | EP | disclosed |
| US-6455520-B1 | TUMOR NECROSIS FACTOR AND INTERLEUKIN INHIBITORS; ANTIINFLAMMATORY AGENTS, ANTIALLERGENS; BONE DISORDERS | ASTRA ZENECA AB (SE) | 2002-09-24 | — | — | US | disclosed |
| EP-1115707-A1 | BENZAMIDE DERIVATIVES AND THER USE AS CYTOKINE INHIBITORS | AstraZeneca AB (SE) | 2001-07-18 | — | — | EP | disclosed |
| WO-2000018738-A1 | BENZAMIDE DERIVATIVES AND THEIR USE AS CYTOKINE INHIBITORS | ASTRAZENECA AB (SE) | 2000-04-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110312935-A1 | 1H-Benz Imidazole-5-Carboxamides As Anti-Inflammatory Agents | MAPRE2, MAPRE1, H1-4 | SMN1; SMN2 3446/4885RAB9A 867/4885ALDH1A1 1202/4885 |
| US-20090048238-A1 | NOVEL BIARYL DERIVATIVES | CCR3, CCRL2, CCR2 | SMN1; SMN2 3658/4885RAB9A 3065/4885ALDH1A1 1202/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.