Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 5/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | CFD | P00746 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16211767 | 1.00 | P2RX7 (0.40) | P2RX7HCRTR1MEN1KMT2AALDH1A1 | |
| SCHEMBL16211769 | 1.00 | P2RX7 (0.40) | P2RX7HCRTR1MEN1KMT2AALDH1A1 | |
| SCHEMBL16371852 | 0.88 | P2RX7 (0.44) | P2RX7HCRTR1ALDH1A1GRM5SMN1; SMN2 | |
| SCHEMBL17799684 | 0.88 | P2RX7 (0.44) | P2RX7HCRTR1ALDH1A1GRM5SMN1; SMN2 | |
| SCHEMBL17799744 | 0.84 | TLR7 (0.40) | HCRTR1KDM4EGRM5 | |
| SCHEMBL17799746 | 0.83 | MC1R (0.45) | P2RX7HCRTR1KMT2AGAA | |
| SCHEMBL17799639 | 0.78 | GRM5 (0.55) | P2RX7HCRTR1ALDH1A1GRM5SMN1; SMN2 | |
| SCHEMBL17799652 | 0.78 | HCRTR1 (0.45) | P2RX7HCRTR1ALDH1A1GRM5SMN1; SMN2 | |
| SCHEMBL16372105 | 0.78 | GRM5 (0.55) | P2RX7HCRTR1ALDH1A1GRM5SMN1; SMN2 | |
| SCHEMBL28050006 | 0.76 | SLC9A1 (0.45) | P2RX7CFDSMN1; SMN2MALT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160075653-A1 | NEMATICIDAL N-(PHENYLCYCLOALKYL)CARBOXAMIDES AND N-(PHENYLCYCLOALKYL)THIOCARBOXAMIDES | BAYER ANIMAL HEALTH GMBH (DE) | 2016-03-17 | — | — | US | disclosed |
| EP-2991487-A1 | NEMATICIDAL N-(PHENYLCYCLOALKYL)CARBOXAMIDES AND N-(PHENYLCYCLOALKYL)THIOCARBOXAMIDES | Bayer CropScience Aktiengesellschaft (DE) | 2016-03-09 | — | — | EP | disclosed |
| WO-2014177487-A9 | NEMATICIDAL N-(PHENYLCYCLOALKYL)CARBOXAMIDES AND N-(PHENYLCYCLOALKYL)THIOCARBOXAMIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2015-12-23 | — | — | WO | disclosed |
| WO-2014177487-A1 | NEMATICIDAL N-(PHENYLCYCLOALKYL)CARBOXAMIDES AND N-(PHENYLCYCLOALKYL)THIOCARBOXAMIDES | BAYER CROPSCIENCE AG (DE) | 2014-11-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160075653-A1 | NEMATICIDAL N-(PHENYLCYCLOALKYL)CARBOXAMIDES AND N-(PHENYLCYCLOALKYL)THIOCARBOXAMIDES | DNPH1, AADAC, NAAA | P2RX7 478/4885HCRTR1 1170/4885MEN1 4839/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.