SCHEMBL28050147

SCHEMBL28050147

CC(C)C1=Cc2c(-c3cc(C(C)(C)C)cc(C(C)(C)C)c3)cccc2C1[SiH3]

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
RXRA P19793 1/20 0.31
RXRB P28702 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27663755 0.88 BRD4 (0.33)
Hydrochloric Acid SCHEMBL28681493 0.86 BRD4 (0.32)
SCHEMBL5860437 0.85 RXRA (0.32) RXRARXRB
SCHEMBL28681492 0.84 BRD4 (0.31)
Hydrochloric Acid SCHEMBL16394842 0.83 RXRA (0.31) RXRARXRB
SCHEMBL28050148 0.82 RXRB (0.33) RXRARXRB
SCHEMBL28050088 0.82 RXRA (0.30) RXRARXRB
SCHEMBL16394843 0.81
SCHEMBL27642869 0.80 CHRNB2 (0.32)
SCHEMBL16394493 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105377905-B Metallocenes and catalyst compositions derived therefrom 埃克森美孚化学专利公司 2018-09-14 CN disclosed
CN-105377905-A Metallocenes and catalyst compositions derived therefrom EXXONMOBIL CHEMICAL PATENTS INC 2016-03-02 CN disclosed