Terephthalamide

Terephthalamide

SCHEMBL28050180

NC(=O)c1ccc(C(N)=O)cc1.NCC1CCCCC1

nearest known ligand 0.63

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PARP10 Q53GL7 5/20 0.63
PARP15 Q460N3 4/20 0.63
PARP2 Q9UGN5 2/20 0.56
CYP2D6 P10635 1/20 0.49
CYP2C9 P11712 1/20 0.45
NPC1 O15118 1/20 0.44
CDK1 P06493 1/20 0.43
CDK2 P24941 1/20 0.43
KMT2A Q03164 2/20 0.43
CA2 P00918 1/20 0.42
HTR6 P50406 1/20 0.41
MEN1 O00255 1/20 0.41
POLB P06746 1/20 0.41
CHEK2 O96017 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Terephthalamide SCHEMBL17743479 0.87 PARP10 (0.58) PARP10PARP15PARP2CYP2C9KMT2A
Terephthalamide SCHEMBL11200537 0.86 PARP10 (0.65) PARP10PARP15PARP2CYP2C9NPC1
Terephthalamide SCHEMBL197479 0.78 PARP1 (0.60) PARP10PARP15PARP2KMT2ACA2
Terephthalamide SCHEMBL12613686 0.78 PARP1 (0.60) PARP10PARP15PARP2KMT2ACA2
Terephthalamide SCHEMBL472214 0.78 PARP1 (0.60) PARP10PARP15PARP2KMT2ACA2
Decarboxylated Derivative SCHEMBL2813888 0.77 CYP2D6 (0.67) CYP2D6KMT2A
SCHEMBL3090215 0.76 HDAC6 (0.71) PARP10PARP15PARP2NPC1CA2
Terephthalamide SCHEMBL4131585 0.76 PARP1 (0.57) PARP10PARP15PARP2KMT2ACA2
Terephthalamide SCHEMBL5509609 0.76 PARP10 (0.53) PARP10PARP15PARP2CYP2C9KMT2A
SCHEMBL28325439 0.76 GAA (0.60) PARP10PARP15PARP2CYP2C9HTR6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116589852-A Fiber-reinforced polyamide molding compounds 埃姆斯化学股份公司 2023-08-15 CN claimed
CN-116589852-A Fiber-reinforced polyamide molding compounds 埃姆斯化学股份公司 2023-08-15 CN disclosed
CN-105377947-A Method for producing polyamide resin MITSUBISHI GAS CHEMICAL CO 2016-03-02 CN disclosed