Terephthalamide

Terephthalamide

SCHEMBL4131585

C1CCCCC1.N.N.NC(=O)c1ccc(C(N)=O)cc1

nearest known ligand 0.59

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 2/20 0.57
TSHR P16473 2/20 0.57
POLB P06746 1/20 0.57
CYP3A4 P08684 1/20 0.57
MAPT P10636 1/20 0.57
CYP2C19 P33261 1/20 0.57
RECQL P46063 1/20 0.57
BLM P54132 1/20 0.57
PMP22 Q01453 1/20 0.57
HSD17B10 Q99714 1/20 0.57
TDP1 Q9NUW8 1/20 0.57
L3MBTL1 Q9Y468 1/20 0.57
PARP10 Q53GL7 11/20 0.56
PARP15 Q460N3 5/20 0.56
PARP4 Q9UKK3 2/20 0.56
ALDH1A1 P00352 1/20 0.56
KMT2A Q03164 1/20 0.56
PARP14 Q460N5 1/20 0.56
PARP16 Q8N5Y8 1/20 0.56
PARP11 Q9NR21 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Terephthalamide SCHEMBL197479 0.97 PARP1 (0.60) PARP1TSHRPOLBCYP3A4MAPT
Terephthalamide SCHEMBL12613686 0.97 PARP1 (0.60) PARP1TSHRPOLBCYP3A4MAPT
Terephthalamide SCHEMBL472214 0.97 PARP1 (0.60) PARP1TSHRPOLBCYP3A4MAPT
Terephthalamide SCHEMBL28199658 0.91 PARP1 (0.67) PARP1TSHRPOLBCYP3A4MAPT
Terephthalamide SCHEMBL1906838 0.91 PARP1 (0.67) PARP1TSHRPOLBCYP3A4MAPT
Terephthalamide SCHEMBL23774 0.87 PARP1 (0.71) PARP1TSHRPOLBCYP3A4MAPT
SCHEMBL25338154 0.87 PARP10 (0.65) PARP1TSHRPOLBCYP3A4MAPT
Terephthalamide SCHEMBL10631357 0.86 OPRD1 (0.46) PARP1TSHRPOLBCYP3A4MAPT
Terephthalamide SCHEMBL11512422 0.84 PARP1 (0.67) PARP1TSHRPOLBCYP3A4MAPT
Terephthalamide SCHEMBL7508927 0.84 PARP1 (0.67) PARP1TSHRPOLBCYP3A4MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108475143-A Film touch sensing and preparation method thereof 东友精细化工有限公司 2018-08-31 CN disclosed
US-20090008682-A1 Light-Receiving Device SUMITOMO BAKELITE CO., LTD. (JP) 2009-01-08 US disclosed
EP-1804296-B1 LIGHT-RECEIVING DEVICE SUMITOMO BAKELITE CO (JP) 2008-10-01 EP disclosed
EP-1804296-A1 LIGHT-RECEIVING DEVICE SUMITOMO BAKELITE CO., LTD. (JP) 2007-07-04 EP disclosed
US-6531529-B2 Mixture of aromatic polyamide, organohalogen compound and addition polymer SOLVAY ADVANCED POLYMERS, L.L.C. 2003-03-11 US disclosed
US-20010053819-A1 Flame retardant anti-drip polyamide compositions SOLVAY ADVANCED POLYMERS, LLC 2001-12-20 US disclosed
US-6207745-B1 COMPOSITION COMPRISING HIGH TEMPERATURE POLYPHTHALAMIDE, HALOGEN-CONTAINING ORGANIC COMPOUND, ANTI-DRIP COMPONENT COMPRISING POLYMER FORMED FROM AT LEAST ONE ETHYLENICALLY UNSATURATED MONOMER AND AT LEAST ONE CARBOXYLIC ACID BP AMOCO CORPORATION 2001-03-27 US disclosed
EP-0807665-B1 Flame retardant high temperature polyphthalamides having improved thermal stability BP AMOCO CORP (US) 2000-07-12 EP disclosed
EP-0986614-A1 FLAME RETARDANT ANTI-DRIP POLYAMIDE COMPOSITIONS BP AMOCO CORPORATION (US) 2000-03-22 EP disclosed
WO-1999040157-A1 FLAME RETARDANT ANTI-DRIP POLYAMIDE COMPOSITIONS BP AMOCO CORPORATION (US) 1999-08-12 WO disclosed
US-5773500-A BROMINATED POLYSTYRENE WITH ANTIMONY COMPOUND AND MOLDING, CALCIUM OXIDE, MAGNESIUM OXIDE AND ZINC OXIDE AMOCO CORPORATION (US) 1998-06-30 US disclosed
EP-0807665-A2 Flame retardant high temperature polyphthalamides having improved thermal stability AMOCO CORPORATION (US) 1997-11-19 EP disclosed
EP-0540890-A1 Copolyamides of terephthalic acid, hexamethylene diamine and 2-methyl pentamethylene diamine HOECHST CELANESE CORPORATION (US) 1993-05-12 EP disclosed
EP-0191548-B1 HIGH IMPACT RESISTANT POLYAMIDE E.I. DU PONT DE NEMOURS AND COMPANY (US) 1993-03-24 EP disclosed
US-4851473-A SYNTHETIC RUBBER TOUGHENER E. I. DU PONT DE NEMOURS AND COMPANY (US) 1989-07-25 US disclosed
EP-0191548-A2 High impact resistant polyamide E.I. DU PONT DE NEMOURS AND COMPANY (US) 1986-08-20 EP disclosed