Terephthalamide

Terephthalamide

SCHEMBL11200537

C1CCC(CC2CCCCC2)CC1.NC(=O)c1ccc(C(N)=O)cc1

nearest known ligand 0.65

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP10 Q53GL7 6/20 0.65
PARP15 Q460N3 5/20 0.65
PARP2 Q9UGN5 2/20 0.57
CYP2C9 P11712 1/20 0.46
NPC1 O15118 1/20 0.45
CDK2 P24941 2/20 0.44
CDK1 P06493 1/20 0.44
CA2 P00918 1/20 0.43
HTR6 P50406 1/20 0.42
KMT2A Q03164 2/20 0.42
MEN1 O00255 1/20 0.42
POLB P06746 1/20 0.42
CHEK2 O96017 1/20 0.42
ALDH1A1 P00352 1/20 0.42
PARP14 Q460N5 1/20 0.42
PARP16 Q8N5Y8 1/20 0.42
PARP11 Q9NR21 1/20 0.42
PARP4 Q9UKK3 1/20 0.42
CCNA2 P20248 1/20 0.41
CCNA1 P78396 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Terephthalamide SCHEMBL28050180 0.86 PARP10 (0.63) PARP10PARP15PARP2CYP2C9NPC1
Terephthalamide SCHEMBL250831 0.82 PARP10 (0.54) PARP10PARP15PARP2CYP2C9CA2
Urea SCHEMBL27625501 0.80 ALOX5 (0.52) PARP10PARP15CA2KMT2A
Terephthalamide SCHEMBL12613686 0.80 PARP1 (0.60) PARP10PARP15PARP2CA2KMT2A
Terephthalamide SCHEMBL197479 0.80 PARP1 (0.60) PARP10PARP15PARP2CA2KMT2A
Terephthalamide SCHEMBL472214 0.80 PARP1 (0.60) PARP10PARP15PARP2CA2KMT2A
SCHEMBL3090215 0.78 HDAC6 (0.71) PARP10PARP15PARP2NPC1CA2
Terephthalamide SCHEMBL4131585 0.78 PARP1 (0.57) PARP10PARP15PARP2CA2KMT2A
Terephthalamide SCHEMBL5509609 0.78 PARP10 (0.53) PARP10PARP15PARP2CYP2C9CA2
Terephthalamide SCHEMBL17743479 0.77 PARP10 (0.58) PARP10PARP15PARP2CYP2C9KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0085175-A1 Transparent cyclic and/or aromatic copolyamide with nylon 6 ALLIED CORPORATION (US) 1983-08-10 EP claimed
CN-105331099-B Fire-resistant polyamide composite 杜邦公司 2018-02-23 CN disclosed