Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | HTR6 | P50406 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | MPO | P05164 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | DHFR | P00374 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfanilamide SCHEMBL27917543 | 0.88 | KMT2A (0.55) | KMT2AMEN1LMNAHTR6TSHR | |
| SCHEMBL28117507 | 0.73 | ESR1 (0.61) | KMT2AMEN1LMNAHTR6TSHR | |
| SCHEMBL27923422 | 0.73 | MEN1 (0.51) | KMT2AMEN1LMNAHTR6TSHR | |
| SCHEMBL10731094 | 0.73 | CA1 (0.50) | KMT2AMEN1PKMAURKA | |
| SCHEMBL28050238 | 0.71 | MEN1 (0.40) | KMT2AMEN1LMNAHTR6TSHR | |
| Sulfalene SCHEMBL28404 | 0.71 | MEN1 (1.00) | KMT2AMEN1LMNATSHRESR1 | |
| Sulfalene SCHEMBL1893333 | 0.71 | MEN1 (1.00) | KMT2AMEN1LMNATSHRESR1 | |
| Acetaldehyde SCHEMBL4349619 | 0.68 | TSHR (0.50) | KMT2AMEN1LMNAHTR6TSHR | |
| Sulfalene SCHEMBL3964512 | 0.67 | MEN1 (0.90) | KMT2AMEN1LMNATSHRESR1 | |
| Sulfanilamide SCHEMBL28119905 | 0.67 | CA2 (0.52) | KMT2AMEN1LMNAHTR6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105283172-B | Ophthalmic cleaning agent and method thereof | 港大科桥有限公司 | 2018-06-26 | — | — | CN | disclosed |
| CN-107226864-A | Covalent diabodies and application thereof | 宏观基因有限公司 | 2017-10-03 | — | — | CN | disclosed |
| CN-104086540-B | Preparation method for 5,6-DIHYDRO-1H-PYRIDIN-2-ONE COMPOUNDS | 安那迪斯药品股份有限公司 | 2017-04-12 | — | — | CN | disclosed |
| CN-106432503-A | COVALENT DIABODIES AND USES THEREOF | 宏观基因有限公司 | 2017-02-22 | — | — | CN | disclosed |
| CN-106220734-A | Covalent diabodies and application thereof | 宏观基因有限公司 | 2016-12-14 | — | — | CN | disclosed |
| CN-102905703-B | As TLR2 agonist for treating compound (lipopeptid based on cysteine) and the compositions of infection, inflammation, respiratory disorder etc. | 诺华股份有限公司 | 2016-09-28 | — | — | CN | disclosed |
| CN-102369021-B | Covalent diabodies and uses thereof | 宏观基因有限公司 | 2016-09-07 | — | — | CN | disclosed |
| CN-102666874-B | Polypeptide and the using method thereof in the effector function Han Fc district of improvement is shown due to the change of fucosylation degree | MACROGENICS, INC. (US) | 2016-06-01 | — | — | CN | disclosed |
| CN-105283172-A | Ophthalmic cleaning agent and method thereof | VERSITECH LTD | 2016-01-27 | — | — | CN | disclosed |