Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Sulfanilamide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 10/20 | 0.50 |
| ▸ | CA1 | P00915 | 9/20 | 0.50 |
| ▸ | CA9 | Q16790 | 9/20 | 0.50 |
| ▸ | CA12 | O43570 | 8/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | CA7 | P43166 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | CA4 | P22748 | 1/20 | 0.50 |
| ▸ | CA6 | P23280 | 1/20 | 0.50 |
| ▸ | CA5A | P35218 | 1/20 | 0.50 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | AGO2 | Q9UKV8 | 1/20 | 0.50 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MPO | P05164 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetaldehyde SCHEMBL28050240 | 0.88 | KMT2A (0.55) | KMT2AMEN1TSHRLMNAMPO | |
| Sulfanilamide SCHEMBL28119905 | 0.78 | CA2 (0.52) | KMT2AMEN1CA2CA1CA9 | |
| Sulfalene SCHEMBL28086248 | 0.78 | MEN1 (0.90) | KMT2AMEN1CA2CA1CA9 | |
| SCHEMBL10731094 | 0.77 | CA1 (0.50) | KMT2AMEN1CA2CA1CA9 | |
| Sulfanilamide SCHEMBL28725781 | 0.75 | CA2 (0.57) | KMT2AMEN1CA2CA1CA9 | |
| Sulfanilamide SCHEMBL8197658 | 0.75 | CA2 (0.81) | CA2CA1CA9CA12CA14 | |
| SCHEMBL10695768 | 0.73 | MEN1 (0.58) | KMT2AMEN1CA2CA1CA9 | |
| Sulfanilamide SCHEMBL9832120 | 0.73 | CA2 (0.50) | KMT2AMEN1CA2CA1CA9 | |
| Sulfanilamide SCHEMBL28345678 | 0.71 | CA2 (0.47) | KMT2AMEN1CA2CA1CA9 | |
| Sulfanilamide SCHEMBL4188099 | 0.71 | CA2 (0.90) | CA2CA1CA9CA12CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103288763-B | Industrial production method of 2,6-dichloropyrazine | ZHENGZHOU FUYUAN ANIMAL PHARMACEUTICAL CO LTD | 2015-06-03 | — | — | CN | disclosed |
| CN-103288763-A | Industrial production method of 2,6-dichloropyrazine | ZHENGZHOU FUYUAN ANIMAL PHARMACEUTICAL CO LTD | 2013-09-11 | — | — | CN | disclosed |