Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | CRHBP | P24387 | 1/20 | 0.53 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.45 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28690119 | 0.85 | MAPT (0.47) | LMNAMAPTTSHRCRHBPCRHR2 | |
| SCHEMBL2616607 | 0.82 | SMN1; SMN2 (0.52) | LMNAMAPTPOLBSMN1; SMN2RXFP1 | |
| SCHEMBL11841355 | 0.81 | MAPT (0.53) | LMNAMAPTTSHRPOLBSMN1; SMN2 | |
| SCHEMBL16554846 | 0.77 | L3MBTL1 (0.59) | MAPTPOLBL3MBTL1ALDH1A1HPGD | |
| SCHEMBL30474531 | 0.77 | L3MBTL1 (0.59) | MAPTPOLBL3MBTL1ALDH1A1HPGD | |
| SCHEMBL15443213 | 0.77 | GAA (0.57) | LMNAMAPTTSHRCRHBPCRHR2 | |
| SCHEMBL2616605 | 0.76 | KDM4E (0.50) | MAPTPOLBSMN1; SMN2RXFP1L3MBTL1 | |
| SCHEMBL30516210 | 0.76 | KDM4E (0.50) | MAPTPOLBSMN1; SMN2RXFP1L3MBTL1 | |
| SCHEMBL18055499 | 0.76 | MAPT (0.64) | LMNAMAPTSMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL8338087 | 0.75 | ALDH1A1 (0.69) | LMNAMAPTPOLBSMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105189499-A | Can be used as alphavβ6Naphthyridine derivatives of integrin antagonists | GLAXOSMITHKLINE IP DEV CO LTD | 2015-12-23 | — | — | CN | disclosed |