Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.40 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.40 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5306327 | 0.85 | TAAR1 (0.46) | L3MBTL1LMNAMAPK1MEN1KMT2A | |
| SCHEMBL5246607 | 0.84 | MEN1 (0.49) | L3MBTL1LMNAMEN1KMT2AHTR7 | |
| SCHEMBL2096587 | 0.82 | ABCB1 (0.44) | L3MBTL1LMNAMAPK1MEN1KMT2A | |
| SCHEMBL23638842 | 0.81 | ABCB1 (0.61) | KDM4ENR1H3ABCB1 | |
| SCHEMBL30451526 | 0.81 | ABCB1 (0.61) | KDM4ENR1H3ABCB1 | |
| SCHEMBL9289360 | 0.80 | L3MBTL1 (0.50) | L3MBTL1MAPK1MEN1KMT2AHTR7 | |
| SCHEMBL6048564 | 0.79 | HTR7 (0.55) | MEN1KMT2AHTR7 | |
| Hydrochloric Acid SCHEMBL6770600 | 0.78 | HTR7 (0.53) | MEN1KMT2AHTR7 | |
| SCHEMBL27637470 | 0.77 | PTGER4 (0.61) | LMNANPC1PRKCZ | |
| SCHEMBL30452106 | 0.77 | KDM4E (0.57) | L3MBTL1MAPK1MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105384691-A | Preparation method and application of glutaminylcyclase (QC) inhibitor | UNIV SHENZHEN | 2016-03-09 | — | — | CN | disclosed |
| CN-105384692-A | Glutaminyl cyclase inhibitor | UNIV SHENZHEN | 2016-03-09 | — | — | CN | disclosed |