Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT5B | Q4FZB7 | 2/20 | 0.57 |
| ▸ | KMT5C | Q86Y97 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.42 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.41 |
| ▸ | CDK1 | P06493 | 2/20 | 0.41 |
| ▸ | CDK4 | P11802 | 2/20 | 0.41 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.41 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.41 |
| ▸ | CCND1 | P24385 | 2/20 | 0.41 |
| ▸ | CDK2 | P24941 | 2/20 | 0.41 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | NSD2 | O96028 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19917166 | 0.82 | KMT5B (0.52) | KMT5BKMT5CKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL6322745 | 0.75 | KMT5B (0.49) | KMT5BKMT5CKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL28908277 | 0.74 | KMT2A (0.53) | KMT5BKMT5CALDH1A1L3MBTL1PTGS1 | |
| SCHEMBL19917187 | 0.73 | KMT2A (0.56) | KMT5BKMT5CALDH1A1L3MBTL1CDK2 | |
| SCHEMBL2878693 | 0.71 | FADS1 (0.48) | KDM4EALDH1A1NSD2MEN1KMT2A | |
| SCHEMBL13801654 | 0.71 | KDM4E (0.58) | KDM4EALDH1A1L3MBTL1GAAMEN1 | |
| SCHEMBL21920699 | 0.70 | LRRK2 (0.51) | KMT5BKMT5CKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL31368758 | 0.69 | KMT2A (0.47) | KMT5BKMT5CKDM4EPDE10ALRRK2 | |
| SCHEMBL15941242 | 0.69 | KDM4E (0.52) | KMT5BKMT5CKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL8705130 | 0.68 | KMT5B (0.42) | KMT5BKMT5CKDM4EALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105622638-A | Pyrimido or pyridopyridone compound and its preparation method and use | GUANGZHOU KANGSHENG BEITE PHARMACEUTICAL CO LTD | 2016-06-01 | — | — | CN | disclosed |