SCHEMBL28050784

SCHEMBL28050784

c1ccc2nc(Cn3nccn3)c(Cn3nccn3)nc2c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 2/20 0.54
MAPT P10636 3/20 0.42
ALDH1A1 P00352 6/20 0.36
KDM4E B2RXH2 4/20 0.36
HPGD P15428 3/20 0.36
HSD17B10 Q99714 3/20 0.36
TDP1 Q9NUW8 2/20 0.36
GAA P10253 1/20 0.36
KMT2A Q03164 1/20 0.35
NQO2 P16083 1/20 0.34
LMNA P02545 3/20 0.34
MAPK1 P28482 2/20 0.33
PDE10A Q9Y233 1/20 0.33
TSHR P16473 1/20 0.33
CASP1 P29466 1/20 0.33
CASP7 P55210 1/20 0.33
GFER P55789 1/20 0.33
PDE6D O43924 1/20 0.33
ALDH2 P05091 1/20 0.33
ALDH3A1 P30838 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28050798 0.75 PDE10A (0.58) CYP19A1MAPTALDH1A1KDM4EHPGD
SCHEMBL6760656 0.70 CYP19A1 (1.00) CYP19A1MAPTL3MBTL1
SCHEMBL6761838 0.65 POLB (0.56) CYP19A1MAPTALDH1A1HPGDTDP1
SCHEMBL28286005 0.65 CYP19A1 (0.54) CYP19A1MAPTALDH1A1TDP1KMT2A
SCHEMBL3501667 0.64 MAPT (0.53) MAPTALDH1A1KDM4EHPGDHSD17B10
SCHEMBL11399574 0.64 MAPT (0.53) MAPTALDH1A1KDM4EHPGDHSD17B10
SCHEMBL2491027 0.64 KDM4E (0.53) MAPTALDH1A1KDM4EHPGDHSD17B10
SCHEMBL1258591 0.64 MAPT (0.53) MAPTALDH1A1KDM4EHPGDHSD17B10
SCHEMBL30384601 0.64 MAPT (0.53) MAPTALDH1A1KDM4EHPGDHSD17B10
Phenazine SCHEMBL29356959 0.63 MAPT (1.00) MAPTALDH1A1KDM4EHPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105175437-A Triazole quinoxaline cadmium complex and preparation method thereof UNIV NANYANG NORMAL 2015-12-23 CN claimed
CN-105175437-A Triazole quinoxaline cadmium complex and preparation method thereof UNIV NANYANG NORMAL 2015-12-23 CN disclosed
CN-105175437-A Triazole quinoxaline cadmium complex and preparation method thereof UNIV NANYANG NORMAL 2015-12-23 CN disclosed