Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 6/20 | 0.77 |
| ▸ | TNKS | O95271 | 1/20 | 0.73 |
| ▸ | PARP1 | P09874 | 1/20 | 0.73 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.73 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.73 |
| ▸ | CSNK2A2 | P19784 | 4/20 | 0.64 |
| ▸ | CSNK2B | P67870 | 4/20 | 0.64 |
| ▸ | CSNK2A1 | P68400 | 4/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.62 |
| ▸ | HPGD | P15428 | 5/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.62 |
| ▸ | TP53 | P04637 | 3/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.61 |
| ▸ | MPO | P05164 | 1/20 | 0.61 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.61 |
| ▸ | MAOA | P21397 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 7-Methylflavone SCHEMBL9137885 | 0.90 | TP53 (0.77) | MAOBTNKSPARP1TNKS2PARP2 | |
| SCHEMBL28050877 | 0.88 | MAOB (0.62) | MAOBTNKSPARP1TNKS2PARP2 | |
| SCHEMBL28154767 | 0.88 | MAOB (0.86) | MAOBTNKSTNKS2CSNK2A2CSNK2B | |
| SCHEMBL10024074 | 0.86 | CSNK2A2 (0.82) | MAOBTNKSPARP1TNKS2PARP2 | |
| SCHEMBL7593917 | 0.85 | TNKS (1.00) | MAOBTNKSPARP1TNKS2PARP2 | |
| SCHEMBL12757263 | 0.85 | CSNK2A2 (0.74) | MAOBTNKSPARP1TNKS2PARP2 | |
| SCHEMBL22032735 | 0.85 | QPCT (0.69) | MAOBTNKSPARP1TNKS2PARP2 | |
| SCHEMBL9388140 | 0.79 | MAOB (0.68) | MAOBMAOA | |
| 2,7-Dimethylchromone SCHEMBL7600130 | 0.78 | ALDH1A1 (0.64) | MAOBTNKSPARP1TNKS2PARP2 | |
| SCHEMBL5433487 | 0.78 | CSNK2A2 (1.00) | MAOBTNKSCSNK2A2CSNK2BCSNK2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105175375-B | The method that the acetylenic ketone protected using acetoxyl group prepares Benzofurantone compound | 陕西师范大学 | 2017-07-11 | — | — | CN | disclosed |
| CN-105175375-A | Method for preparing benzopyrone compounds through adopting acetoxy protected alkynyl ketone | UNIV SHAANXI NORMAL | 2015-12-23 | — | — | CN | disclosed |