Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 8/20 | 0.74 |
| ▸ | CSNK2B | P67870 | 8/20 | 0.74 |
| ▸ | CSNK2A1 | P68400 | 8/20 | 0.74 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.74 |
| ▸ | POLH | Q9Y253 | 4/20 | 0.74 |
| ▸ | TNKS | O95271 | 4/20 | 0.74 |
| ▸ | PARP1 | P09874 | 4/20 | 0.74 |
| ▸ | TNKS2 | Q9H2K2 | 4/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.68 |
| ▸ | IP6K2 | Q9UHH9 | 4/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.68 |
| ▸ | HPGD | P15428 | 3/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.68 |
| ▸ | MAPT | P10636 | 3/20 | 0.68 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.68 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.68 |
| ▸ | ST6GAL1 | P15907 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL34405 | 0.85 | TNKS (1.00) | CSNK2A2CSNK2BCSNK2A1ALOX5POLH | |
| SCHEMBL29678122 | 0.85 | TNKS (1.00) | CSNK2A2CSNK2BCSNK2A1ALOX5POLH | |
| SCHEMBL28050878 | 0.85 | MAOB (0.77) | CSNK2A2CSNK2BCSNK2A1TNKSPARP1 | |
| SCHEMBL10037938 | 0.84 | CSNK2A2 (0.74) | CSNK2A2CSNK2BCSNK2A1ALOX5POLH | |
| SCHEMBL4160578 | 0.83 | CSNK2A2 (0.81) | CSNK2A2CSNK2BCSNK2A1ALOX5POLH | |
| SCHEMBL2218499 | 0.83 | POLH (0.75) | CSNK2A2CSNK2BCSNK2A1ALOX5POLH | |
| SCHEMBL345706 | 0.81 | TNKS (1.00) | CSNK2A2CSNK2BCSNK2A1ALOX5POLH | |
| SCHEMBL29664745 | 0.81 | TNKS (1.00) | CSNK2A2CSNK2BCSNK2A1ALOX5POLH | |
| SCHEMBL10026574 | 0.80 | POLH (0.74) | CSNK2A2CSNK2BCSNK2A1ALOX5POLH | |
| SCHEMBL4160583 | 0.79 | TNKS (0.64) | CSNK2A2CSNK2BCSNK2A1ALOX5POLH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7910621-B2 | Small molecule antagonists of XIAP family proteins | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2011-03-22 | — | — | US | disclosed |
| US-20080021095-A1 | Small Molecule Antagonists of Xiap Family Proteins | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2008-01-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080021095-A1 | Small Molecule Antagonists of Xiap Family Proteins | XIAP, BIRC5, BIRC3 | CSNK2A2 3792/4885CSNK2B 4032/4885CSNK2A1 3711/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.