Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | GLA | P06280 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.44 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.38 |
| ▸ | PDE2A | O00408 | 2/20 | 0.38 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.36 |
| ▸ | PRKCG | P05129 | 2/20 | 0.36 |
| ▸ | PRKCB | P05771 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL929808 | 0.82 | ALDH1A1 (0.41) | KMT2AKDM4ERAB9AALDH1A1GAA | |
| SCHEMBL929420 | 0.81 | ALDH1A1 (0.40) | KMT2AKDM4ERAB9AALDH1A1GAA | |
| SCHEMBL2544260 | 0.80 | PTPN1 (0.53) | KDM4EALDH1A1GAAHPGDPOLB | |
| SCHEMBL1050913 | 0.78 | GSK3B (0.41) | KMT2AKDM4EGAAPOLBMAPT | |
| SCHEMBL4014126 | 0.76 | KMT2A (0.64) | KMT2AKDM4ERAB9AALDH1A1GAA | |
| SCHEMBL4293393 | 0.75 | KMT2A (0.45) | KMT2AKDM4ERAB9AALDH1A1GAA | |
| SCHEMBL27663126 | 0.75 | PLAUR (0.41) | KDM4ERAB9AALDH1A1GLAHPGD | |
| SCHEMBL5414511 | 0.74 | MAOA (0.39) | KMT2AKDM4EALDH1A1GAAHPGD | |
| SCHEMBL10714445 | 0.74 | PTPN1 (0.50) | KDM4EALDH1A1GAAHPGDPOLB | |
| Ammonia Solution, Strong SCHEMBL27943748 | 0.74 | PLAUR (0.40) | KDM4ERAB9AALDH1A1GLAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105209616-A | HCV NS3 recombinant antigen and mutants thereof for improved antibody detection | ABBOTT LAB | 2015-12-30 | — | — | CN | disclosed |