Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.64 |
| ▸ | MEN1 | O00255 | 6/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.64 |
| ▸ | LMNA | P02545 | 8/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.53 |
| ▸ | HTT | P42858 | 4/20 | 0.53 |
| ▸ | THRB | P10828 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27631130 | 0.86 | ALDH1A1 (0.56) | MAPTMEN1KMT2ALMNACYP1A2 | |
| SCHEMBL27651554 | 0.86 | MEN1 (0.53) | MAPTMEN1KMT2ALMNACYP1A2 | |
| SCHEMBL23148487 | 0.84 | MAPT (0.61) | MAPTMEN1KMT2ALMNACYP1A2 | |
| SCHEMBL28051054 | 0.84 | MAPT (0.67) | MAPTMEN1KMT2ALMNACYP1A2 | |
| SCHEMBL27801439 | 0.84 | MAPT (0.69) | MAPTMEN1KMT2ALMNACYP1A2 | |
| SCHEMBL28051136 | 0.80 | KMT2A (0.58) | MAPTMEN1KMT2ALMNATP53 | |
| SCHEMBL2848203 | 0.80 | MAPT (0.64) | MAPTMEN1KMT2ALMNACYP1A2 | |
| SCHEMBL2846293 | 0.79 | MAPT (0.73) | MAPTMEN1KMT2ALMNACYP1A2 | |
| SCHEMBL27651561 | 0.79 | MAPT (0.69) | MAPTMEN1KMT2ALMNACYP1A2 | |
| SCHEMBL28059516 | 0.78 | KMT2A (0.53) | MAPTMEN1KMT2ALMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105287388-B | High dispersive carbazole sulfonamide derivative and preparation method thereof | 山西普德药业有限公司 | 2019-09-17 | — | — | CN | claimed |
| CN-105418487-A | Carbazole sulfonamide derivative eutectic and preparation method thereof | SHANXI PUDE PHARMACEUTICS CO LTD | 2016-03-23 | — | — | CN | claimed |
| CN-105287388-A | High-dispersion carbazole sulfonamide derivatives and preparation method thereof | SHANXI PUDE PHARMACEUTICS CO LTD | 2016-02-03 | — | — | CN | claimed |
| CN-105287388-B | High dispersive carbazole sulfonamide derivative and preparation method thereof | 山西普德药业有限公司 | 2019-09-17 | — | — | CN | disclosed |
| CN-105418487-A | Carbazole sulfonamide derivative eutectic and preparation method thereof | SHANXI PUDE PHARMACEUTICS CO LTD | 2016-03-23 | — | — | CN | disclosed |
| CN-105287388-A | High-dispersion carbazole sulfonamide derivatives and preparation method thereof | SHANXI PUDE PHARMACEUTICS CO LTD | 2016-02-03 | — | — | CN | disclosed |