Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 2/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 2/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.38 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.38 |
| ▸ | FAP | Q12884 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.36 |
| ▸ | MME | P08473 | 1/20 | 0.36 |
| ▸ | ACE | P12821 | 1/20 | 0.36 |
| ▸ | CPA1 | P15085 | 1/20 | 0.36 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.35 |
| ▸ | ENPEP | Q07075 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28051158 | 1.00 | CTSS (0.42) | CTSSCTSKL3MBTL1DPP4DPP8 | |
| SCHEMBL30051375 | 0.85 | MME (0.51) | CTSSCTSKDPP4DPP8DPP9 | |
| SCHEMBL18913047 | 0.81 | CTSS (0.43) | CTSSCTSKL3MBTL1HTTMME | |
| SCHEMBL18913046 | 0.81 | CTSS (0.43) | CTSSCTSKL3MBTL1HTTMME | |
| SCHEMBL9805212 | 0.81 | TET2 (0.45) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL19319010 | 0.81 | TET2 (0.45) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL16668048 | 0.81 | TET2 (0.45) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL30051352 | 0.78 | MME (0.53) | CTSSCTSKMMEACECPA1 | |
| SCHEMBL31139339 | 0.77 | ALDH1A1 (0.53) | L3MBTL1DPP4DPP8DPP9DPP7 | |
| SCHEMBL31139335 | 0.77 | ALDH1A1 (0.53) | L3MBTL1DPP4DPP8DPP9DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105218632-A | As peptide or plan peptide, the Preparation Method And The Use of transglutaminase inhibitor | ZEDIRA GMBH | 2016-01-06 | — | — | CN | disclosed |