Known targets — ChEMBL curated mechanism
GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHMGCRMMP1MMP13MMP7MMP8PTGS1PTGS2ileSpolrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acrylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acrylic Acid SCHEMBL311614 | 1.00 | LMNA (0.47) | LMNATSHRALDH1A1FGFR4CA1 | |
| Acrylic Acid SCHEMBL27900867 | 0.96 | LMNA (0.44) | LMNATSHRALDH1A1FGFR4CA1 | |
| Acrylic Acid SCHEMBL27868965 | 0.96 | LMNA (0.44) | LMNATSHRALDH1A1FGFR4CA1 | |
| Acrylic Acid SCHEMBL10838320 | 0.96 | LMNA (0.44) | LMNATSHRALDH1A1FGFR4CA1 | |
| Acrylic Acid SCHEMBL5173948 | 0.96 | LMNA (0.44) | LMNATSHRALDH1A1FGFR4CA1 | |
| Acrylic Acid SCHEMBL27647775 | 0.96 | LMNA (0.53) | LMNATSHRALDH1A1FGFR4CA1 | |
| Acrylic Acid SCHEMBL28547140 | 0.96 | — | — | |
| Acrylic Acid SCHEMBL29516833 | 0.96 | LMNA (0.50) | LMNATSHRALDH1A1FGFR4CA1 | |
| Acrylic Acid SCHEMBL28051258 | 0.93 | LMNA (0.41) | LMNATSHRALDH1A1FGFR4CA1 | |
| Acrylic Acid SCHEMBL16257 | 0.92 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1760260-A | Antibacterial high water absorption polymer composite material and preparation method thereof | INST OF PHYSICS & CHEMISTRY TE (CN) | 2006-04-19 | — | — | CN | disclosed |