Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 1/20 | 0.44 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.44 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.37 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.36 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.36 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.36 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.36 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | EDNRA | P25101 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9732243 | 0.79 | KAT6A (0.41) | SLC1A3SLC1A2SLC1A1ALDH1A1HSD11B1 | |
| SCHEMBL27349975 | 0.77 | SLC1A3 (0.42) | SLC1A3SLC1A2SLC1A1ALDH1A1HSD11B1 | |
| SCHEMBL7504532 | 0.77 | LMNA (0.42) | SLC1A3SLC1A2SLC1A1ALDH1A1HSD11B1 | |
| SCHEMBL6097627 | 0.77 | LMNA (0.42) | SLC1A3SLC1A2SLC1A1ALDH1A1HSD11B1 | |
| SCHEMBL31575071 | 0.75 | SLC1A3 (0.39) | SLC1A3SLC1A2SLC1A1ALDH1A1HSD11B1 | |
| SCHEMBL8742943 | 0.75 | LMNA (0.41) | SLC1A3SLC1A2SLC1A1ALDH1A1HSD11B1 | |
| SCHEMBL562674 | 0.75 | SLC1A3 (0.39) | SLC1A3SLC1A2SLC1A1ALDH1A1HSD11B1 | |
| SCHEMBL6282158 | 0.73 | SLC1A3 (0.41) | SLC1A3SLC1A2SLC1A1ALDH1A1HSD11B1 | |
| SCHEMBL7999434 | 0.73 | SLC1A3 (0.38) | SLC1A3SLC1A2SLC1A1ALDH1A1HSD11B1 | |
| SCHEMBL27403973 | 0.73 | CA1 (0.58) | SLC1A3SLC1A2SLC1A1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105237549-B | A kind of synthetic method of sirolimus 40- ether derivants | 浙江医药股份有限公司新昌制药厂 | 2018-03-09 | — | — | CN | claimed |
| CN-105237549-A | Synthetic method for sirolimus 40-ether derivative | ZHEJIANG MED XINCHANG PHARM | 2016-01-13 | — | — | CN | claimed |
| CN-105237549-A | Synthetic method for sirolimus 40-ether derivative | ZHEJIANG MED XINCHANG PHARM | 2016-01-13 | — | — | CN | disclosed |