SCHEMBL7999434

SCHEMBL7999434

Cc1ccccc1S(=O)(=O)C(I)I.[NaH]

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC1A3 P43003 1/20 0.38
SLC1A2 P43004 1/20 0.38
SLC1A1 P43005 1/20 0.38
RAPGEF4 Q8WZA2 1/20 0.38
LMNA P02545 1/20 0.37
MCOLN3 Q8TDD5 1/20 0.37
ALDH1A1 P00352 4/20 0.37
KDM4E B2RXH2 3/20 0.37
L3MBTL1 Q9Y468 2/20 0.37
TP53 P04637 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
TSHR P16473 1/20 0.36
ACHE P22303 1/20 0.36
HSD11B1 P28845 1/20 0.36
RXFP1 Q9HBX9 1/20 0.36
EDNRA P25101 1/20 0.36
HTR2A P28223 1/20 0.35
HTR2C P28335 1/20 0.35
MEN1 O00255 1/20 0.35
ESR1 P03372 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31575071 0.98 SLC1A3 (0.39) SLC1A3SLC1A2SLC1A1RAPGEF4LMNA
SCHEMBL562674 0.98 SLC1A3 (0.39) SLC1A3SLC1A2SLC1A1RAPGEF4LMNA
SCHEMBL6097627 0.78 LMNA (0.42) SLC1A3SLC1A2SLC1A1RAPGEF4LMNA
SCHEMBL7504532 0.78 LMNA (0.42) SLC1A3SLC1A2SLC1A1RAPGEF4LMNA
SCHEMBL27492534 0.78 LMNA (0.40) SLC1A3SLC1A2SLC1A1RAPGEF4LMNA
SCHEMBL8742943 0.77 LMNA (0.41) SLC1A3SLC1A2SLC1A1RAPGEF4LMNA
SCHEMBL9732243 0.77 KAT6A (0.41) SLC1A3SLC1A2SLC1A1RAPGEF4LMNA
SCHEMBL6282158 0.75 SLC1A3 (0.41) SLC1A3SLC1A2SLC1A1RAPGEF4LMNA
SCHEMBL752591 0.73 HSD11B1 (0.45) LMNAALDH1A1L3MBTL1TP53TDP1
SCHEMBL28051399 0.73 SLC1A3 (0.44) SLC1A3SLC1A2SLC1A1RAPGEF4LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1011609-A4 COMPOSITIONS FOR COSMETIC APPLICATIONS MEDLOGIC GLOBAL CORP (US) 2000-08-16 EP disclosed
EP-1011609-A1 COMPOSITIONS FOR COSMETIC APPLICATIONS MedLogic Global Corporation (US) 2000-06-28 EP disclosed
WO-1998050005-A1 COMPOSITIONS FOR COSMETIC APPLICATIONS MEDLOGIC GLOBAL CORPORATION (US) 1998-11-12 WO disclosed