Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 1/20 | 0.41 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | ESR1 | P03372 | 2/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.37 |
| ▸ | ITGAV | P06756 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10650374 | 0.87 | MMP2 (0.40) | LMNAHSD11B1ALDH1A1KMT2AGAA | |
| SCHEMBL7504532 | 0.83 | LMNA (0.42) | SLC1A3SLC1A2SLC1A1LMNAMCOLN3 | |
| SCHEMBL6097627 | 0.83 | LMNA (0.42) | SLC1A3SLC1A2SLC1A1LMNAMCOLN3 | |
| SCHEMBL8742943 | 0.81 | LMNA (0.41) | SLC1A3SLC1A2SLC1A1LMNAMCOLN3 | |
| Isopropyl Alcohol SCHEMBL28113936 | 0.79 | MYC (0.47) | SLC1A3SLC1A2SLC1A1LMNAMCOLN3 | |
| SCHEMBL28193048 | 0.79 | CA12 (0.49) | SLC1A3SLC1A2SLC1A1LMNAMCOLN3 | |
| SCHEMBL27492534 | 0.78 | LMNA (0.40) | SLC1A3SLC1A2SLC1A1LMNAMCOLN3 | |
| SCHEMBL10934294 | 0.78 | MYC (0.46) | SLC1A3SLC1A2SLC1A1LMNAMCOLN3 | |
| SCHEMBL11207535 | 0.78 | GAA (0.54) | GAA | |
| SCHEMBL4432528 | 0.78 | CA1 (0.52) | HSD11B1L3MBTL1KMT2APOLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6906046-B2 | Pharmaceutical uses and synthesis of benzobicyclooctanes | CELLTECH R & D INC. (US) | 2005-06-14 | — | — | US | disclosed |
| US-20030069305-A1 | Pharmaceutical uses and synthesis of benzobicyclooctanes | CELLTECH R & D, INC. | 2003-04-10 | — | — | US | disclosed |
| WO-2002051851-A2 | PHARMACEUTICAL USES AND SYNTHESIS OF BENZOBICYCLOOCTANES | CELLTECH R & D, INC. (US) | 2002-07-04 | — | — | WO | disclosed |
| EP-0163996-A1 | 2,2-Dimethyl-3-formylcyclopropanes and process for their preparation | BAYER AG (DE) | 1985-12-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030069305-A1 | Pharmaceutical uses and synthesis of benzobicyclooctanes | CXCL8, CASP8, IL18 | SLC1A3 4797/4885SLC1A2 4760/4885SLC1A1 4753/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.