Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.47 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | CDK2 | P24941 | 2/20 | 0.44 |
| ▸ | SYK | P43405 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.41 |
| ▸ | CDK1 | P06493 | 1/20 | 0.41 |
| ▸ | CDK4 | P11802 | 1/20 | 0.41 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.41 |
| ▸ | CCND1 | P24385 | 1/20 | 0.41 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.41 |
| ▸ | CDK9 | P50750 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | BCR | P11274 | 1/20 | 0.41 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.41 |
| ▸ | FLT3 | P36888 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28037898 | 0.87 | KCNH2 (0.54) | KCNH3SCN9AKCNH2CDK2SYK | |
| SCHEMBL28051482 | 0.84 | IDH2 (0.54) | KCNH3CRHR1FLT3PRKCDCAMK2B | |
| SCHEMBL28051498 | 0.83 | IDH2 (0.53) | KCNH3SCN9AKCNH2CDK2SYK | |
| SCHEMBL27935508 | 0.81 | NR1I2 (0.56) | KCNH3KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL28564314 | 0.80 | MAPT (0.52) | SCN9AKCNH2CDK2SYKKDM4E | |
| SCHEMBL28051330 | 0.80 | ADORA3 (0.59) | KCNH3SCN9AKCNH2CDK2SYK | |
| SCHEMBL301485 | 0.78 | AURKA (0.51) | CDK1FLT3PRKCDCAMK2BCAMK2G | |
| SCHEMBL6033558 | 0.77 | APP (0.48) | KCNH3SCN9AKCNH2CDK2SYK | |
| SCHEMBL13064959 | 0.77 | KDM4E (0.69) | KCNH3SCN9AKCNH2CDK2SYK | |
| SCHEMBL6978430 | 0.75 | LMNA (0.52) | KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105294588-A | Fluorotriazine-containing derivative, and preparation method and use thereof | WUHAN INST TECHNOLOGY | 2016-02-03 | — | — | CN | disclosed |