Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH2 | P48735 | 2/20 | 0.53 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.50 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | KIF11 | P52732 | 1/20 | 0.47 |
| ▸ | CDK2 | P24941 | 2/20 | 0.47 |
| ▸ | SYK | P43405 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | BCR | P11274 | 1/20 | 0.43 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.43 |
| ▸ | CDK1 | P06493 | 1/20 | 0.43 |
| ▸ | CDK4 | P11802 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28037898 | 0.92 | KCNH2 (0.54) | IDH2KCNH3SCN9AKCNH2CDK2 | |
| SCHEMBL28051330 | 0.84 | ADORA3 (0.59) | KCNH3SCN9AKCNH2CDK2SYK | |
| SCHEMBL28051487 | 0.83 | KCNH3 (0.47) | IDH2KCNH3SCN9AKCNH2CDK2 | |
| SCHEMBL27916780 | 0.81 | LMNA (0.66) | IDH2KCNH3KIF11MEN1LMNA | |
| SCHEMBL6033558 | 0.81 | APP (0.48) | KCNH3SCN9AKCNH2CDK2SYK | |
| SCHEMBL13064959 | 0.81 | KDM4E (0.69) | KCNH3SCN9AKCNH2CDK2SYK | |
| SCHEMBL28051514 | 0.78 | KCNH3 (0.79) | IDH2KCNH3KIF11MEN1LMNA | |
| SCHEMBL28051482 | 0.78 | IDH2 (0.54) | IDH2KCNH3KIF11MEN1LMNA | |
| SCHEMBL21496175 | 0.78 | RAB9A (0.56) | SCN9AKCNH2CDK2SYKKDM4E | |
| SCHEMBL14800688 | 0.77 | KCNH2 (0.45) | KCNH3SCN9AKCNH2CDK2SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105294588-A | Fluorotriazine-containing derivative, and preparation method and use thereof | WUHAN INST TECHNOLOGY | 2016-02-03 | — | — | CN | disclosed |