SCHEMBL28051645

SCHEMBL28051645

CC[C@H](C)Cc1ccccc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 2/20 0.57
SIGMAR1 Q99720 5/20 0.56
TAAR1 Q96RJ0 4/20 0.56
SLC6A2 P23975 3/20 0.56
SLC6A4 P31645 2/20 0.56
SLC6A3 Q01959 2/20 0.56
MAOA P21397 1/20 0.56
CYP2A6 P11509 1/20 0.56
ADORA2A P29274 1/20 0.56
ADORA1 P30542 1/20 0.56
SLC18A2 Q05940 1/20 0.52
CYP2D6 P10635 1/20 0.52
EPHX1 P07099 1/20 0.48
TP53 P04637 1/20 0.48
ADRA2B P18089 1/20 0.47
ADRA2C P18825 1/20 0.47
HTR2A P28223 1/20 0.47
ADRA1A P35348 1/20 0.47
OPRK1 P41145 1/20 0.47
KCNH2 Q12809 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL3082124 1.00 TRPA1 (0.57) TRPA1SIGMAR1TAAR1SLC6A2SLC6A4
SCHEMBL199315 1.00 TRPA1 (0.57) TRPA1SIGMAR1TAAR1SLC6A2SLC6A4
Hydrazine SCHEMBL1006192 0.95 SIGMAR1 (0.58) TRPA1SIGMAR1TAAR1SLC6A2SLC6A4
SCHEMBL6547498 0.91 SIGMAR1 (0.50) TRPA1SIGMAR1TAAR1SLC6A2SLC6A4
SCHEMBL9427581 0.88 TRPA1 (0.47) TRPA1SIGMAR1TAAR1SLC6A2SLC6A4
SCHEMBL4785594 0.87 SIGMAR1 (0.64) TRPA1SIGMAR1TAAR1SLC6A2SLC6A4
SCHEMBL28048725 0.87 SIGMAR1 (0.47) TRPA1SIGMAR1TAAR1SLC6A2SLC6A4
SCHEMBL8061416 0.87 SIGMAR1 (0.47) TRPA1SIGMAR1TAAR1SLC6A2SLC6A4
SCHEMBL19700920 0.83 CHKA (0.50) TRPA1SIGMAR1TAAR1SLC6A2SLC6A4
SCHEMBL8072287 0.82 SIGMAR1 (0.58) TRPA1SIGMAR1TAAR1SLC6A2SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105330534-A Method used for preparing (S)-(+)-4-(2-methylbutyl)benzoic acid HEBEI YANUO CHEMICAL CO LTD 2016-02-17 CN claimed
CN-105330534-A Method used for preparing (S)-(+)-4-(2-methylbutyl)benzoic acid HEBEI YANUO CHEMICAL CO LTD 2016-02-17 CN disclosed
CN-105330534-A Method used for preparing (S)-(+)-4-(2-methylbutyl)benzoic acid HEBEI YANUO CHEMICAL CO LTD 2016-02-17 CN disclosed