SCHEMBL28048725

SCHEMBL28048725

CC[C@H](C)Cc1ccc(-c2ccccc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 3/20 0.47
MME P08473 5/20 0.47
ACE P12821 5/20 0.47
CPA1 P15085 4/20 0.47
ACE2 Q9BYF1 4/20 0.47
TRPA1 O75762 1/20 0.46
TAAR1 Q96RJ0 4/20 0.45
SLC6A2 P23975 2/20 0.43
MAOA P21397 1/20 0.43
SLC6A4 P31645 1/20 0.43
SLC6A3 Q01959 1/20 0.43
CYP2A6 P11509 1/20 0.43
ADORA2A P29274 1/20 0.43
ADORA1 P30542 1/20 0.43
SRR Q9GZT4 1/20 0.43
PSAT1 Q9Y617 1/20 0.43
ALDH1A1 P00352 1/20 0.43
CYP1A2 P05177 1/20 0.43
CYP2D6 P10635 1/20 0.43
ACP3 P15309 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8061416 1.00 SIGMAR1 (0.47) SIGMAR1MMEACECPA1ACE2
SCHEMBL199315 0.87 TRPA1 (0.57) SIGMAR1TRPA1TAAR1SLC6A2MAOA
SCHEMBL28051645 0.87 TRPA1 (0.57) SIGMAR1TRPA1TAAR1SLC6A2MAOA
Benzene SCHEMBL3082124 0.87 TRPA1 (0.57) SIGMAR1TRPA1TAAR1SLC6A2MAOA
SCHEMBL16374643 0.85 CYP17A1 (0.39) SIGMAR1TAAR1SLC6A4CYP2A6ACACB
SCHEMBL10720375 0.84 SIGMAR1 (0.46) SIGMAR1MMEACECPA1ACE2
SCHEMBL18559857 0.83 CYP19A1 (0.41) SIGMAR1TAAR1CYP2A6CYP1A2ACACB
SCHEMBL6547498 0.83 SIGMAR1 (0.50) SIGMAR1TRPA1TAAR1SLC6A2MAOA
SCHEMBL24181347 0.83 TRPA1 (0.37) SIGMAR1MMEACECPA1ACE2
SCHEMBL8689678 0.83 PTGS1 (0.43) MMEACECPA1ACE2CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108912842-A A kind of multiple anti-fake liquid crystal ink, Preparation method and use 北京化工大学 2018-11-30 CN disclosed
CN-105198712-A Method of preparing S-(+)-4-(2-methylbutyl) xenol HEBEI YANUO CHEMICAL CO LTD 2015-12-30 CN disclosed