Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.40 |
| ▸ | NCF1 | P14598 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NNMT | P40261 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28051783 | 0.82 | KDM4E (0.36) | ALDH1A1HPGDKDM4ERAB9AMAPT | |
| SCHEMBL28051777 | 0.80 | MAPT (0.41) | ALDH1A1HPGDHCAR3KDM4ERAB9A | |
| SCHEMBL16506185 | 0.79 | PTGER4 (0.46) | PTGER4ALDH1A1HCAR3NCF1KDM4E | |
| SCHEMBL28271305 | 0.75 | HCAR3 (0.46) | PTGER4ALDH1A1HPGDHCAR3KDM4E | |
| SCHEMBL28051766 | 0.74 | ADRA1D (0.48) | PTGER4ALDH1A1HPGDHCAR3KDM4E | |
| SCHEMBL16505728 | 0.73 | PTGER4 (0.40) | PTGER4ALDH1A1HCAR3NCF1MAPT | |
| SCHEMBL16517756 | 0.71 | PTGER4 (0.50) | PTGER4ALDH1A1HCAR3NCF1KDM4E | |
| SCHEMBL4539617 | 0.70 | KDM4E (0.54) | PTGER4ALDH1A1HPGDKDM4ERAB9A | |
| SCHEMBL5591756 | 0.69 | PTGER4 (0.47) | PTGER4ALDH1A1HCAR3KDM4ERAB9A | |
| SCHEMBL28051782 | 0.69 | PTGER4 (0.47) | PTGER4ALDH1A1HPGDHCAR3NCF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105658639-A | Alkynyl alcohols and methods of use | 豪夫迈·罗氏有限公司 | 2016-06-08 | — | — | CN | disclosed |