SCHEMBL28052039

SCHEMBL28052039

CCCCOC(=O)C(CC)=C1CCCCC1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.41
ATM Q13315 1/20 0.39
TSHR P16473 6/20 0.39
NAAA Q02083 1/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
TDP1 Q9NUW8 1/20 0.38
HPGD P15428 1/20 0.37
SMN1; SMN2 Q16637 3/20 0.36
KMT2A Q03164 2/20 0.36
NPC1 O15118 1/20 0.36
TP53 P04637 1/20 0.36
MAPT P10636 1/20 0.36
NFKB1 P19838 1/20 0.36
RAB9A P51151 1/20 0.36
NFKB2 Q00653 1/20 0.36
RELA Q04206 1/20 0.36
ESR1 P03372 5/20 0.36
LMNA P02545 3/20 0.36
CYP1A2 P05177 2/20 0.36
CYP2C19 P33261 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL971459 0.85 NAAA (0.52) ALDH1A1TSHRNAAANPC1TP53
SCHEMBL20262457 0.83 ALDH1A1 (0.44) ALDH1A1ATMTSHRNAAAL3MBTL1
SCHEMBL13517350 0.83 ALDH1A1 (0.44) ALDH1A1ATMTSHRNAAAL3MBTL1
SCHEMBL13518257 0.81 ALDH1A1 (0.45) ALDH1A1ATMTSHRNAAAL3MBTL1
SCHEMBL20262484 0.81 ALDH1A1 (0.45) ALDH1A1ATMTSHRNAAAL3MBTL1
SCHEMBL28052037 0.77 FAAH (0.37) ALDH1A1NAAAL3MBTL1TDP1KMT2A
SCHEMBL13517259 0.75 ALDH1A1 (0.37) ALDH1A1ATMTSHRL3MBTL1TDP1
SCHEMBL13517949 0.74 ALDH1A1 (0.36) ALDH1A1ATMTSHRL3MBTL1TDP1
SCHEMBL13517672 0.73 ALDH1A1 (0.38) ALDH1A1ATMTSHRL3MBTL1TDP1
SCHEMBL4911652 0.73 TSHR (0.47) ALDH1A1TSHRNAAAHPGDLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105418363-A Synthetic method for 4-tertiary butyl cyclohexaneacetic acid SHANDONG CHUANCHENG PHARMACEUTICAL CO LTD 2016-03-23 CN disclosed