Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3034960 | 0.81 | L3MBTL1 (0.60) | L3MBTL1KDM4EPKMTSHRMAPK1 | |
| SCHEMBL4542872 | 0.79 | L3MBTL1 (0.42) | L3MBTL1KDM4EPKMTSHRMAPK1 | |
| SCHEMBL8635622 | 0.79 | F12 (0.49) | L3MBTL1KDM4EPKMTSHRMAPK1 | |
| SCHEMBL6910808 | 0.79 | ALDH1A1 (0.46) | L3MBTL1KDM4EPKMTSHRMAPK1 | |
| SCHEMBL515403 | 0.78 | LMNA (0.43) | L3MBTL1KDM4EPKMTSHRMAPK1 | |
| SCHEMBL11412871 | 0.76 | ALDH1A1 (0.49) | L3MBTL1KDM4EPKMTSHRMAPK1 | |
| SCHEMBL11412874 | 0.76 | ALDH1A1 (0.49) | L3MBTL1KDM4EPKMTSHRMAPK1 | |
| Hydrochloric Acid SCHEMBL11407926 | 0.73 | ALDH1A1 (0.50) | L3MBTL1KDM4EPKMHTTLMNA | |
| Hydrochloric Acid SCHEMBL11407925 | 0.73 | ALDH1A1 (0.50) | L3MBTL1KDM4EPKMHTTLMNA | |
| SCHEMBL146503 | 0.71 | CYP1A2 (0.56) | KDM4ETSHRHTTLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105348301-A | Phenothiazines intermediate and preparation method therefor | WUHAN INST TECHNOLOGY | 2016-02-24 | — | — | CN | disclosed |
| CN-105294735-A | Phenothiazine organic small molecule donor and preparation method thereof | WUHAN INST TECHNOLOGY | 2016-02-03 | — | — | CN | disclosed |