Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ADCY10 | Q96PN6 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10784087 | 0.79 | ALDH1A1 (0.48) | PTGS1PTGS2MAPTCYP2C9POLB | |
| SCHEMBL30657896 | 0.76 | PTGS1 (0.41) | PTGS1PTGS2MAPTCYP2C9POLB | |
| SCHEMBL7354585 | 0.76 | PTGS1 (0.41) | PTGS1PTGS2MAPTCYP2C9POLB | |
| SCHEMBL30049391 | 0.76 | GAA (0.45) | PTGS1PTGS2MAPTCYP2C9POLB | |
| SCHEMBL27508658 | 0.74 | TSHR (0.40) | ALOX5CYP2C9TDP1TP53ALDH1A1 | |
| SCHEMBL1408606 | 0.74 | ALDH1A1 (0.41) | PTGS1PTGS2CYP2C9TP53ALDH1A1 | |
| SCHEMBL8398705 | 0.73 | POLB (0.54) | PTGS1PTGS2MAPTCYP2C9POLB | |
| SCHEMBL1408822 | 0.73 | TDP1 (0.39) | PTGS1PTGS2TDP1TP53ALDH1A1 | |
| SCHEMBL2313482 | 0.71 | TDP1 (0.42) | PTGS1PTGS2ALOX5MAPTTDP1 | |
| SCHEMBL809528 | 0.70 | TP53 (0.41) | MAPTTDP1TP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105315181-A | Synthetic method for sulfo trisubstituted alkenes compound | UNIV HUNAN | 2016-02-10 | — | — | CN | disclosed |