Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 2/20 | 0.45 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | PLG | P00747 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | CTSG | P08311 | 1/20 | 0.39 |
| ▸ | CMA1 | P23946 | 1/20 | 0.39 |
| ▸ | CTRC | Q99895 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | GSK3A | P49840 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | FABP4 | P15090 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29115280 | 0.76 | HPGD (0.60) | TLR7HPGDALDH1A1CYP3A4MEN1 | |
| SCHEMBL3385411 | 0.75 | DAO (0.49) | DAOHPGDALDH1A1CYP3A4F2 | |
| SCHEMBL28052100 | 0.74 | DAO (0.45) | DAOCXCR2TLR7F2PLG | |
| SCHEMBL6476334 | 0.72 | DAO (0.46) | DAOCXCR2HPGDALDH1A1CYP3A4 | |
| SCHEMBL7837587 | 0.72 | DAO (0.46) | DAOCXCR2HPGDALDH1A1CYP3A4 | |
| SCHEMBL3391548 | 0.71 | LMNA (0.44) | ALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL21055329 | 0.70 | MEN1 (0.51) | DAOCXCR2HPGDALDH1A1CYP3A4 | |
| SCHEMBL2573713 | 0.67 | L3MBTL1 (0.45) | TLR7HPGDALDH1A1CYP3A4MEN1 | |
| SCHEMBL11619322 | 0.65 | MEN1 (0.50) | DAOCXCR2MEN1KMT2A | |
| SCHEMBL7475187 | 0.65 | HPGD (0.62) | HPGDALDH1A1CYP3A4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105348213-A | Preparation method for beta-fluoroalkyl-beta-amino acids compound | UNIV WUHAN TECH | 2016-02-24 | — | — | CN | disclosed |