Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MPI | P34949 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7833292 | 0.72 | NOTUM (0.48) | LMNAMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL13860451 | 0.72 | AURKA (0.57) | LMNAMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL3264283 | 0.72 | ALDH1A1 (0.50) | LMNAMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL31503514 | 0.72 | MEN1 (0.50) | LMNAMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL27115574 | 0.72 | LMNA (0.47) | LMNAMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL486072 | 0.71 | LMNA (0.70) | LMNAMEN1KMT2ACRHBPCRHR2 | |
| SCHEMBL10749180 | 0.71 | ALDH1A1 (0.47) | LMNAMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL28052223 | 0.71 | DAO (0.45) | MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL10503709 | 0.70 | LMNA (0.47) | LMNAMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL265945 | 0.69 | SMN1; SMN2 (0.52) | LMNAMEN1KMT2AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2151433-A1 | Alkoxypyrazoles and the process for their preparation | Institut Pasteur (FR) | 2010-02-10 | — | — | EP | disclosed |