Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19668245 | 0.74 | KLKB1 (0.45) | KLKB1KLK1 | |
| SCHEMBL28052335 | 0.73 | CYP11B1 (0.42) | KLKB1KLK1 | |
| SCHEMBL16486803 | 0.70 | KLKB1 (0.48) | KLKB1KLK1 | |
| SCHEMBL28052788 | 0.69 | KLKB1 (0.47) | KLKB1KLK1 | |
| SCHEMBL28071587 | 0.67 | ALDH1A1 (0.38) | — | |
| SCHEMBL14671613 | 0.67 | LMNA (0.39) | KLKB1KLK1 | |
| SCHEMBL15759268 | 0.66 | KLKB1 (0.51) | KLKB1KLK1 | |
| SCHEMBL28013163 | 0.66 | — | — | |
| SCHEMBL28516700 | 0.66 | — | — | |
| SCHEMBL19513505 | 0.65 | KLKB1 (0.52) | KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105452240-A | Heterocyclic derivates | KALVISTA PHARMACEUTICALS LTD | 2016-03-30 | — | — | CN | disclosed |