Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 13/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 13/20 | 0.42 |
| ▸ | KLKB1 | P03952 | 6/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | KLK1 | P06870 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28052255 | 0.73 | KLKB1 (0.36) | KLKB1KLK1 | |
| SCHEMBL16486803 | 0.72 | KLKB1 (0.48) | KLKB1KCNH2KLK1 | |
| SCHEMBL16246788 | 0.70 | CYP11B1 (0.49) | CYP11B1CYP11B2KLKB1KLK1 | |
| SCHEMBL14671613 | 0.69 | LMNA (0.39) | KLKB1KLK1 | |
| SCHEMBL15759268 | 0.69 | KLKB1 (0.51) | KLKB1KLK1 | |
| SCHEMBL27981466 | 0.67 | TBXAS1 (0.33) | CYP11B1CYP11B2 | |
| SCHEMBL3822319 | 0.67 | CYP11B1 (0.52) | CYP11B1CYP11B2 | |
| SCHEMBL11918416 | 0.67 | KCNH2 (0.60) | CYP11B1CYP11B2KLKB1KCNH2 | |
| SCHEMBL28052788 | 0.67 | KLKB1 (0.47) | KLKB1KLK1 | |
| SCHEMBL19068681 | 0.66 | KLKB1 (0.47) | KLKB1KLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105452240-A | Heterocyclic derivates | KALVISTA PHARMACEUTICALS LTD | 2016-03-30 | — | — | CN | disclosed |