Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | PRKAB2 | O43741 | 2/20 | 0.52 |
| ▸ | PRKAG1 | P54619 | 2/20 | 0.52 |
| ▸ | PRKAA2 | P54646 | 2/20 | 0.52 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.52 |
| ▸ | PRKAG3 | Q9UGI9 | 2/20 | 0.52 |
| ▸ | PRKAG2 | Q9UGJ0 | 2/20 | 0.52 |
| ▸ | PRKAB1 | Q9Y478 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | FAAH | O00519 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1018777 | 0.93 | MEN1 (0.57) | MEN1KMT2ALMNASMN1; SMN2MAPK1 | |
| SCHEMBL12955106 | 0.89 | PRKAB2 (0.55) | MAPK1PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL1019721 | 0.89 | HIF1A (0.53) | MEN1KMT2APRKAB2PRKAG1PRKAA2 | |
| SCHEMBL12954825 | 0.88 | MEN1 (0.46) | MEN1KMT2ALMNASMN1; SMN2MAPK1 | |
| SCHEMBL1017900 | 0.87 | MEN1 (0.53) | MEN1KMT2ALMNASMN1; SMN2MAPK1 | |
| SCHEMBL1019433 | 0.86 | LMNA (0.46) | MEN1KMT2ALMNASMN1; SMN2MAPK1 | |
| SCHEMBL1020459 | 0.86 | PRKAB2 (0.47) | MEN1KMT2ALMNASMN1; SMN2MAPK1 | |
| SCHEMBL1021758 | 0.86 | PRKAB2 (0.53) | MEN1KMT2AMAPK1PRKAB2PRKAG1 | |
| Trifluoroacetic Acid SCHEMBL1018850 | 0.86 | PRKAB2 (0.57) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 | |
| SCHEMBL12954974 | 0.85 | DRD2 (0.47) | KMT2AFAAHSIGMAR1MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101848899-B | As the N-benzyl of LXR conditioning agent, N '-aryl carbonyl bridged piperazine derivatives | MERCK SHARP & DOHME B.V. (NL) | 2016-03-02 | — | — | CN | disclosed |