Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PDE9A | O76083 | 1/20 | 0.34 |
| ▸ | IDH1 | O75874 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16102191 | 0.80 | ERN1 (0.38) | NPC1MAPTRAB9APRMT6MEN1 | |
| SCHEMBL28600542 | 0.77 | P2RX7 (0.38) | MEN1LMNATHRBBLMKMT2A | |
| SCHEMBL12854044 | 0.77 | NPC1 (0.44) | NPC1MAPTRAB9APRMT6MEN1 | |
| SCHEMBL2051188 | 0.76 | NPC1 (0.47) | NPC1MAPTRAB9APRMT6LMNA | |
| SCHEMBL12380848 | 0.76 | NPC1 (0.43) | NPC1MAPTRAB9APRMT6NPSR1 | |
| SCHEMBL28589894 | 0.74 | MEN1 (0.35) | MEN1LMNATHRBBLMKMT2A | |
| SCHEMBL28917820 | 0.74 | MEN1 (0.35) | MEN1LMNATHRBBLMKMT2A | |
| SCHEMBL26028892 | 0.73 | NPC1 (0.42) | NPC1MAPTRAB9APRMT6MEN1 | |
| SCHEMBL8663944 | 0.73 | NPC1 (0.42) | NPC1MAPTRAB9APRMT6 | |
| SCHEMBL8664692 | 0.73 | RAB9A (0.42) | NPC1MAPTRAB9APRMT6MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105263920-A | Fungicidal carboxamides | DU PONT | 2016-01-20 | — | — | CN | disclosed |