Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | F10 | P00742 | 7/20 | 0.40 |
| ▸ | F2 | P00734 | 2/20 | 0.39 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 3/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8663944 | 0.85 | NPC1 (0.42) | RAB9ANPC1MAPTF10F2 | |
| SCHEMBL15637195 | 0.77 | ALDH1A1 (0.40) | LMNATP53HTTALDH1A1SMN1; SMN2 | |
| SCHEMBL26028892 | 0.77 | NPC1 (0.42) | RAB9ANPC1MAPTPRMT6LMNA | |
| SCHEMBL7775611 | 0.75 | DRD2 (0.39) | RAB9AF10PTGS2LMNATP53 | |
| SCHEMBL27785533 | 0.75 | NPC1 (0.43) | RAB9ANPC1MAPTPRMT6LMNA | |
| SCHEMBL12854044 | 0.74 | NPC1 (0.44) | RAB9ANPC1MAPTPRMT6LMNA | |
| SCHEMBL2051188 | 0.73 | NPC1 (0.47) | RAB9ANPC1MAPTPRMT6LMNA | |
| SCHEMBL12380848 | 0.73 | NPC1 (0.43) | RAB9ANPC1MAPTPRMT6HTT | |
| SCHEMBL1528319 | 0.73 | MAPT (0.52) | RAB9ANPC1MAPTPRMT6PTGS2 | |
| SCHEMBL28052675 | 0.73 | NPC1 (0.44) | RAB9ANPC1MAPTPRMT6LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0830133-A1 | THERAPEUTIC COMPOSITION FOR ARTHRITIS | Takeda Chemical Industries, Ltd. (JP) | 1998-03-25 | — | — | EP | disclosed |
| WO-1996033717-A1 | THERAPEUTIC COMPOSITION FOR ARTHRITIS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-10-31 | — | — | WO | disclosed |