Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 2/20 | 0.47 |
| ▸ | NOS3 | P29474 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.39 |
| ▸ | TYMP | P19971 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | STAT3 | P40763 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.35 |
| ▸ | CDK1 | P06493 | 2/20 | 0.35 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.35 |
| ▸ | GSK3A | P49840 | 2/20 | 0.35 |
| ▸ | GSK3B | P49841 | 2/20 | 0.35 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.35 |
| ▸ | ESR1 | P03372 | 2/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27672334 | 1.00 | NOS2 (0.47) | NOS2NOS3KCNH2TYMPTDP1 | |
| SCHEMBL28129531 | 0.93 | NOS2 (0.50) | NOS2NOS3TYMPTDP1L3MBTL1 | |
| SCHEMBL14569374 | 0.79 | NOS2 (0.59) | NOS2NOS3L3MBTL1RAB9ASMN1; SMN2 | |
| SCHEMBL21806238 | 0.79 | NOS2 (0.77) | NOS2NOS3KCNH2MAPTRAB9A | |
| SCHEMBL19310672 | 0.77 | TDP1 (0.35) | NOS2NOS3KCNH2TDP1L3MBTL1 | |
| SCHEMBL10456083 | 0.77 | TYR (0.44) | KCNH2TDP1L3MBTL1NPC1MAPT | |
| SCHEMBL28052894 | 0.77 | TYR (0.44) | KCNH2TDP1L3MBTL1NPC1MAPT | |
| SCHEMBL4453790 | 0.77 | TYMP (0.41) | KCNH2TYMPNPC1MAPTSTAT3 | |
| SCHEMBL22791948 | 0.75 | LIPG (0.40) | KCNH2TDP1L3MBTL1NPC1MAPT | |
| SCHEMBL20752742 | 0.75 | NOS2 (0.44) | NOS2NOS3SMN1; SMN2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105473715-A | Modified amadoriase and method for producing same, surfactant resistance improver for amadoriase, and composition for measurement of HbA1c using same | KIKKOMAN CORP | 2016-04-06 | — | — | CN | claimed |
| CN-105473715-A | Modified amadoriase and method for producing same, surfactant resistance improver for amadoriase, and composition for measurement of HbA1c using same | KIKKOMAN CORP | 2016-04-06 | — | — | CN | disclosed |