Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 2/20 | 0.44 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | STAT3 | P40763 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10456083 | 1.00 | TYR (0.44) | TYRLIPGKCNH2MAPTTDP1 | |
| SCHEMBL28124885 | 0.93 | CTRC (0.39) | TYRL3MBTL1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL22791948 | 0.84 | LIPG (0.40) | TYRLIPGKCNH2MAPTTDP1 | |
| SCHEMBL6999496 | 0.82 | TYR (0.46) | TYRLIPGKCNH2MAPTTDP1 | |
| SCHEMBL24228676 | 0.79 | TYR (0.44) | TYRLIPGKCNH2MAPTTDP1 | |
| SCHEMBL19310672 | 0.79 | TDP1 (0.35) | TYRLIPGKCNH2MAPTTDP1 | |
| SCHEMBL8916740 | 0.79 | TLR8 (0.40) | LIPGKCNH2MAPTTDP1CYP3A4 | |
| SCHEMBL21806239 | 0.79 | NOS2 (0.46) | TYRLIPGMAPTMEN1KMT2A | |
| SCHEMBL16828251 | 0.79 | TYR (0.38) | TYRLIPGKCNH2MAPTTDP1 | |
| Hydrochloric Acid SCHEMBL28538588 | 0.79 | TYR (0.44) | TYRLIPGKCNH2MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105473715-A | Modified amadoriase and method for producing same, surfactant resistance improver for amadoriase, and composition for measurement of HbA1c using same | KIKKOMAN CORP | 2016-04-06 | — | — | CN | claimed |
| CN-105473715-A | Modified amadoriase and method for producing same, surfactant resistance improver for amadoriase, and composition for measurement of HbA1c using same | KIKKOMAN CORP | 2016-04-06 | — | — | CN | disclosed |