SCHEMBL28053012

SCHEMBL28053012

CCCCCON(CC)CCS(=O)(=O)O

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 9/20 0.36
CA2 P00918 9/20 0.36
CA9 Q16790 8/20 0.36
CA12 O43570 3/20 0.35
CA7 P43166 3/20 0.35
CA14 Q9ULX7 3/20 0.35
CA3 P07451 2/20 0.35
CA4 P22748 2/20 0.35
CA6 P23280 2/20 0.35
CA5A P35218 2/20 0.35
CA5B Q9Y2D0 2/20 0.35
RECQL P46063 2/20 0.34
EPHX2 P34913 2/20 0.34
GLA P06280 1/20 0.34
HPGD P15428 1/20 0.34
TSHR P16473 1/20 0.34
MAPK1 P28482 1/20 0.34
BLM P54132 1/20 0.34
S1PR1 P21453 1/20 0.34
S1PR3 Q99500 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28158511 0.77 TP53 (0.35) CA1CA2EPHX2S1PR1S1PR3
SCHEMBL4810103 0.75 DNM1 (0.37) CA1CA2CA9CA12CA7
SCHEMBL28126402 0.75 DNM1 (0.42) CA1CA2CA9CA12CA7
SCHEMBL8574590 0.74 THRB (0.37) CA1CA2CA9CA12CA7
SCHEMBL8026102 0.74 MEN1 (0.45) CA1CA2CA9CA12TSHR
SCHEMBL3045373 0.72 THRB (0.42) CA1CA2CA9CA12CA7
SCHEMBL7153290 0.72 PTGS1 (0.31) BLM
SCHEMBL8979941 0.71 DNM1 (0.42) CA1CA2CA9CA12TSHR
SCHEMBL17180573 0.71 EPHX2 (0.38) CA1CA2CA9CA12CA7
SCHEMBL8979944 0.71 ADRB2 (0.36) CA1CA2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105682634-A Use of a combination of taurine or a derivative thereof and a grape extract for improving the quality of nails 伊诺瓦实验室 2016-06-15 CN disclosed