Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL28053018

CCCCCC(N)CC.O=C(O)C(F)(F)F

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.44
MAPT P10636 1/20 0.44
S1PR1 P21453 9/20 0.43
S1PR3 Q99500 9/20 0.43
S1PR2 O95136 8/20 0.43
S1PR4 O95977 4/20 0.43
GRIK1 P39086 2/20 0.43
GRIK2 Q13002 2/20 0.43
SLC1A2 P43004 1/20 0.43
SLC1A1 P43005 1/20 0.43
FAAH O00519 3/20 0.42
S1PR5 Q9H228 3/20 0.42
GPR84 Q9NQS5 2/20 0.41
CES2 O00748 1/20 0.41
CES1 P23141 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL23850595 0.98 ALDH1A1 (0.47) ALDH1A1MAPTS1PR1S1PR3S1PR2
Trifluoroacetic Acid SCHEMBL28484990 0.98 ALDH1A1 (0.47) ALDH1A1MAPTS1PR1S1PR3S1PR2
Trifluoroacetic Acid SCHEMBL27742918 0.98 ALDH1A1 (0.47) ALDH1A1MAPTS1PR1S1PR3S1PR2
Trifluoroacetic Acid SCHEMBL28627218 0.87 ALDH1A1 (0.61) ALDH1A1MAPTS1PR1S1PR3S1PR2
Trifluoroacetic Acid SCHEMBL31581663 0.86 ALDH1A1 (0.44) ALDH1A1S1PR1S1PR3S1PR2GRIK1
Trifluoroacetic Acid SCHEMBL28159128 0.85 GSR (0.38) ALDH1A1MAPT
Oxalic Acid SCHEMBL16467153 0.84 ALDH1A1 (0.50) ALDH1A1MAPTS1PR1S1PR3S1PR2
Tuaminoheptane SCHEMBL23174984 0.83 OPRM1 (0.61) MAPTS1PR1S1PR3S1PR2GRIK1
Acetic Acid SCHEMBL7566097 0.82 ALDH1A1 (0.53) ALDH1A1MAPTS1PR1S1PR3S1PR2
Acetic Acid SCHEMBL5231341 0.82 ALDH1A1 (0.53) ALDH1A1MAPTS1PR1S1PR3S1PR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117858879-A CDK2/4/6 inhibitor and preparation method and application thereof 南京再明医药有限公司 2024-04-09 CN disclosed
CN-116529246-A N- [ (1, 3-benzoxazol-2-yl) -heterocycle ] amide derivatives for the treatment and prevention of hepatitis b virus infection 豪夫迈·罗氏有限公司 2023-08-01 CN disclosed
CN-103717571-B The tetracycline compound that 9-amino methyl replaces KBP BIOSCIENCES Co.,Ltd. (CN) 2016-01-13 CN disclosed