Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | DPP8 | Q6V1X1 | 4/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.40 |
| ▸ | DPP4 | P27487 | 2/20 | 0.40 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.38 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.38 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.38 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.38 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL27860844 | 0.87 | DPP8 (0.41) | DPP8DPP7DPP4SLC1A3SLC1A2 | |
| Trifluoroacetic Acid SCHEMBL28053018 | 0.86 | ALDH1A1 (0.44) | ALDH1A1GRIK1SLC1A2SLC1A1GRIK2 | |
| Trifluoroacetic Acid SCHEMBL19555428 | 0.86 | DPP8 (0.39) | DPP8DPP7DPP4S1PR1S1PR3 | |
| Trifluoroacetic Acid SCHEMBL28484990 | 0.85 | ALDH1A1 (0.47) | ALDH1A1GRIK1GRIK2S1PR1S1PR3 | |
| Trifluoroacetic Acid SCHEMBL27742918 | 0.85 | ALDH1A1 (0.47) | ALDH1A1GRIK1GRIK2S1PR1S1PR3 | |
| Trifluoroacetic Acid SCHEMBL23850595 | 0.85 | ALDH1A1 (0.47) | ALDH1A1GRIK1GRIK2S1PR1S1PR3 | |
| Trifluoroacetic Acid SCHEMBL28159128 | 0.82 | GSR (0.38) | ALDH1A1DPP8DPP7DPP4 | |
| Acetic Acid SCHEMBL7707557 | 0.82 | ALDH1A1 (0.50) | ALDH1A1GRIK1SLC1A3SLC1A2SLC1A1 | |
| Trifluoroacetic Acid SCHEMBL28627218 | 0.81 | ALDH1A1 (0.61) | ALDH1A1GRIK1GRIK2S1PR1S1PR3 | |
| Trifluoroacetic Acid SCHEMBL29386325 | 0.81 | GABRP (0.46) | ALDH1A1DPP8DPP7DPP4GRIK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025106386-A1 | A CYCLIC PEPTIDE FOR TRAPPING INTERLEUKIN-1 BETA | MERCK SHARP & DOHME LLC (US) | 2025-05-22 | — | — | WO | disclosed |