Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.70 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.70 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.70 |
| ▸ | LMNA | P02545 | 4/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | APEX1 | P27695 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2735040 | 0.89 | KMT2A (0.87) | KMT2ACYP1A2CYP2C19LMNAL3MBTL1 | |
| SCHEMBL11319016 | 0.87 | KMT2A (0.69) | KMT2ACYP1A2CYP2C19LMNAL3MBTL1 | |
| SCHEMBL28930415 | 0.86 | KMT2A (0.52) | KMT2ACYP1A2CYP2C19LMNAL3MBTL1 | |
| SCHEMBL28053361 | 0.84 | APEX1 (0.57) | KMT2ACYP1A2CYP2C19LMNAL3MBTL1 | |
| SCHEMBL4182426 | 0.84 | ALDH1A1 (0.62) | KMT2ACYP1A2CYP2C19LMNAL3MBTL1 | |
| SCHEMBL28053365 | 0.84 | HPGD (0.68) | KMT2ALMNAL3MBTL1MAPTAPEX1 | |
| SCHEMBL15686617 | 0.84 | KMT2A (0.74) | KMT2ACYP1A2CYP2C19LMNAL3MBTL1 | |
| SCHEMBL29285015 | 0.83 | APEX1 (0.64) | KMT2ACYP1A2CYP2C19LMNAL3MBTL1 | |
| SCHEMBL12472363 | 0.83 | KMT2A (0.72) | KMT2ACYP1A2CYP2C19LMNAL3MBTL1 | |
| SCHEMBL6357013 | 0.83 | KMT2A (1.00) | KMT2ACYP1A2CYP2C19LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105294597-A | Benzothiazine derivative, and synthetic method and application thereof | UNIV EAST CHINA NORMAL | 2016-02-03 | — | — | CN | disclosed |