Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 8/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | APEX1 | P27695 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 3/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11319016 | 0.87 | KMT2A (0.69) | HPGDAPEX1TP53GLALMNA | |
| SCHEMBL28053295 | 0.84 | KMT2A (0.70) | HPGDALDH1A1KDM4ESMN1; SMN2APEX1 | |
| SCHEMBL28053361 | 0.84 | APEX1 (0.57) | HPGDALDH1A1KDM4ESMN1; SMN2APEX1 | |
| SCHEMBL4182426 | 0.84 | ALDH1A1 (0.62) | HPGDALDH1A1KDM4ESMN1; SMN2APEX1 | |
| SCHEMBL1034235 | 0.84 | HPGD (0.72) | HPGDALDH1A1KDM4EHSD17B10SMN1; SMN2 | |
| SCHEMBL19746688 | 0.84 | HPGD (0.67) | HPGDALDH1A1SMN1; SMN2TP53GLA | |
| SCHEMBL29285015 | 0.83 | APEX1 (0.64) | HPGDALDH1A1HSD17B10SMN1; SMN2APEX1 | |
| SCHEMBL7823453 | 0.83 | APEX1 (0.84) | HPGDALDH1A1KDM4EHSD17B10SMN1; SMN2 | |
| SCHEMBL15686093 | 0.81 | HPGD (0.68) | HPGDALDH1A1KDM4EHSD17B10SMN1; SMN2 | |
| SCHEMBL29433995 | 0.81 | HPGD (1.00) | HPGDALDH1A1KDM4EHSD17B10SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105294597-B | Benzothiazine derivatives and its synthetic method and application | 华东师范大学 | 2017-11-24 | — | — | CN | disclosed |
| CN-105294597-A | Benzothiazine derivative, and synthetic method and application thereof | UNIV EAST CHINA NORMAL | 2016-02-03 | — | — | CN | disclosed |