Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.44 |
| ▸ | FEN1 | P39748 | 1/20 | 0.44 |
| ▸ | HSD17B14 | Q9BPX1 | 1/20 | 0.43 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27598108 | 0.86 | HSP90AB1 (0.51) | MAPTL3MBTL1SMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL23041052 | 0.84 | L3MBTL1 (0.50) | MAPTL3MBTL1SMN1; SMN2ERCC5FEN1 | |
| SCHEMBL14241162 | 0.84 | NR1H4 (0.53) | MAPTL3MBTL1SMN1; SMN2ERCC5FEN1 | |
| SCHEMBL7194494 | 0.83 | HPGD (0.46) | MAPTL3MBTL1SMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL8085526 | 0.83 | L3MBTL1 (0.49) | MAPTL3MBTL1SMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL27540917 | 0.83 | MAPT (0.49) | MAPTL3MBTL1SMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL14241374 | 0.83 | KAT6A (0.50) | MAPTL3MBTL1SMN1; SMN2ALDH1A1HDAC6 | |
| SCHEMBL9679486 | 0.81 | SMN1; SMN2 (0.65) | MAPTL3MBTL1SMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL24454658 | 0.81 | ALDH1A1 (0.50) | MAPTSMN1; SMN2HPGDALDH1A1BCL2L1 | |
| SCHEMBL6005391 | 0.81 | L3MBTL1 (0.69) | MAPTL3MBTL1SMN1; SMN2HPGDERCC5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105377253-A | Anti-viral compounds, pharmaceutical compositions, and methods of use thereof | KINETA INC | 2016-03-02 | — | — | CN | disclosed |