Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.65 |
| ▸ | MAPT | P10636 | 3/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13814813 | 0.82 | SMN1; SMN2 (0.65) | SMN1; SMN2L3MBTL1MAPTALDH1A1HPGD | |
| SCHEMBL28053324 | 0.81 | MAPT (0.50) | SMN1; SMN2L3MBTL1MAPTALDH1A1HPGD | |
| SCHEMBL30989217 | 0.81 | L3MBTL1 (0.62) | SMN1; SMN2L3MBTL1MAPTALDH1A1HPGD | |
| SCHEMBL10803948 | 0.81 | SMN1; SMN2 (0.62) | SMN1; SMN2L3MBTL1MAPTALDH1A1HPGD | |
| SCHEMBL1906865 | 0.81 | L3MBTL1 (0.62) | SMN1; SMN2L3MBTL1MAPTALDH1A1HPGD | |
| SCHEMBL8532327 | 0.79 | SMN1; SMN2 (0.69) | SMN1; SMN2L3MBTL1MAPTALDH1A1HPGD | |
| SCHEMBL13267783 | 0.79 | MAPT (1.00) | SMN1; SMN2L3MBTL1MAPTALDH1A1HPGD | |
| SCHEMBL1928026 | 0.79 | MAPT (1.00) | SMN1; SMN2L3MBTL1MAPTALDH1A1HPGD | |
| SCHEMBL6249474 | 0.78 | HPGD (0.68) | L3MBTL1MAPTALDH1A1HPGDLMNA | |
| SCHEMBL8699645 | 0.78 | CA12 (0.59) | SMN1; SMN2MAPTALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5149866-A | Reacting aryl alkyl ketone with sulfur, an amine and a catalyst to produce a mixture containing a thioamide, sulfur, and a sulfur containing compound basification to produce an acid salt and acidification | HOECHST CELANESE CORPORATION (US) | 1992-09-22 | — | — | US | disclosed |