Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 7/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28374320 | 0.82 | MAPT (0.48) | RAB9ANPC1ALDH1A1NPSR1HTT | |
| SCHEMBL7982074 | 0.80 | TSPO (0.44) | RAB9ANPC1ALOX12ALDH1A1NPSR1 | |
| SCHEMBL11620656 | 0.72 | NPSR1 (0.42) | RAB9ANPC1ALDH1A1NPSR1HTT | |
| SCHEMBL11117629 | 0.70 | HTT (0.41) | RAB9ANPC1ALDH1A1NPSR1HTT | |
| SCHEMBL13338594 | 0.70 | ALDH1A1 (0.42) | RAB9ANPC1ALOX12ALDH1A1NPSR1 | |
| SCHEMBL28966865 | 0.70 | KDM4E (0.39) | RAB9ANPC1ALDH1A1NPSR1HTT | |
| SCHEMBL845316 | 0.70 | NPC1 (0.40) | RAB9ANPC1ALDH1A1NPSR1HTT | |
| SCHEMBL4298743 | 0.69 | HTT (0.46) | RAB9ANPC1ALDH1A1NPSR1HTT | |
| SCHEMBL7985644 | 0.69 | TRPM8 (0.42) | RAB9ANPC1ALDH1A1NPSR1HTT | |
| SCHEMBL9585217 | 0.68 | ALDH1A1 (0.45) | RAB9ANPC1ALDH1A1NPSR1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102471300-B | Compositions and methods for enhancing viral potency | OTTAWA HOSPITAL RESEARCH INSTITUTE (CA) | 2016-04-13 | — | — | CN | disclosed |