Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT2 | O15382 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | IKBKB | O14920 | 5/20 | 0.43 |
| ▸ | CHUK | O15111 | 3/20 | 0.43 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.41 |
| ▸ | CDC7 | O00311 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30030003 | 0.85 | BCAT2 (0.50) | BCAT2IKBKBKEAP1NFE2L2MAPT | |
| SCHEMBL8102370 | 0.84 | BCAT2 (0.69) | BCAT2IKBKBCHUKMEN1KMT2A | |
| SCHEMBL2567641 | 0.82 | BCAT2 (0.71) | BCAT2SLC6A4SLC6A3IKBKBCHUK | |
| Hydrochloric Acid SCHEMBL5797256 | 0.81 | BCAT2 (0.69) | BCAT2SLC6A4SLC6A3IKBKBCHUK | |
| SCHEMBL17803632 | 0.80 | SLC6A4 (0.51) | BCAT2SLC6A4SLC6A3IKBKBCHUK | |
| SCHEMBL4177888 | 0.80 | MAPK9 (0.45) | GRM2MEN1JAK2KMT2ASLC9A1 | |
| SCHEMBL21629968 | 0.78 | BCAT2 (0.46) | BCAT2SLC6A4SLC6A3IKBKBCHUK | |
| SCHEMBL27940786 | 0.77 | IKBKB (0.47) | BCAT2SLC6A4SLC6A3IKBKBCHUK | |
| SCHEMBL28186096 | 0.77 | IKBKB (0.42) | BCAT2SLC6A4SLC6A3IKBKBCHUK | |
| SCHEMBL30370009 | 0.76 | BCAT2 (0.57) | BCAT2SLC6A4SLC6A3IKBKBCHUK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105294597-A | Benzothiazine derivative, and synthetic method and application thereof | UNIV EAST CHINA NORMAL | 2016-02-03 | — | — | CN | claimed |
| CN-105294597-A | Benzothiazine derivative, and synthetic method and application thereof | UNIV EAST CHINA NORMAL | 2016-02-03 | — | — | CN | disclosed |