Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | TP53 | P04637 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.37 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.37 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27721618 | 0.84 | RAB9A (0.50) | ALDH1A1KMT2AMEN1LMNAMAPT | |
| SCHEMBL23399736 | 0.83 | ALDH1A1 (0.42) | ALDH1A1GAALMNAMAPTTP53 | |
| SCHEMBL27984253 | 0.81 | ELANE (0.38) | ALDH1A1GAAKMT2AMEN1MAPT | |
| SCHEMBL27678182 | 0.80 | KDM4E (0.52) | KMT2AMEN1LMNASMN1; SMN2HPGD | |
| SCHEMBL27676109 | 0.80 | RAB9A (0.49) | ALDH1A1GAAKMT2AMEN1LMNA | |
| SCHEMBL28784327 | 0.78 | MAPK14 (0.48) | KMT2AMEN1MAPTSMN1; SMN2HPGD | |
| SCHEMBL27707913 | 0.77 | HPGD (0.46) | ALDH1A1LMNAMAPTTP53SMN1; SMN2 | |
| SCHEMBL28766880 | 0.75 | MAPT (0.56) | ALDH1A1GAAKMT2AMEN1LMNA | |
| SCHEMBL23398388 | 0.74 | MAPT (0.42) | ALDH1A1GAAKMT2AMEN1LMNA | |
| SCHEMBL27728424 | 0.73 | ADK (0.34) | ALDH1A1TP53HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105377847-A | Kinase inhibitors | CHIESI FARM SPA | 2016-03-02 | — | — | CN | disclosed |