Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL234076 | 0.82 | ALDH1A1 (0.41) | HSD11B1HSD11B2ALDH1A1TP53TSHR | |
| Hydrochloric Acid SCHEMBL15194419 | 0.80 | ALDH1A1 (0.40) | HSD11B1HSD11B2ALDH1A1TP53TSHR | |
| Hydrochloric Acid SCHEMBL15194272 | 0.80 | ALDH1A1 (0.40) | HSD11B1HSD11B2ALDH1A1TP53TSHR | |
| SCHEMBL6138350 | 0.79 | ALDH1A1 (0.39) | HSD11B1HSD11B2ALDH1A1TP53TSHR | |
| SCHEMBL28582679 | 0.78 | HSD11B1 (0.35) | HSD11B1HSD11B2ALDH1A1TP53TSHR | |
| SCHEMBL6138323 | 0.77 | ALDH1A1 (0.53) | ALDH1A1TP53TSHRHTTPOLB | |
| Hydrochloric Acid SCHEMBL15194218 | 0.77 | ALDH1A1 (0.38) | HSD11B1HSD11B2ALDH1A1TP53TSHR | |
| SCHEMBL14858388 | 0.75 | ALDH1A1 (0.40) | HSD11B1HSD11B2ALDH1A1TP53TSHR | |
| SCHEMBL232028 | 0.75 | NPSR1 (0.39) | HSD11B1HSD11B2ALDH1A1HTTGAA | |
| SCHEMBL5633342 | 0.73 | ALDH1A1 (0.54) | ALDH1A1TP53TSHRHTTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105263933-B | A kind of simultaneously [1,2 a] benzazolyl compounds and preparation method thereof and the application in medicine of pyrazine | 埃斯蒂维实验室股份有限公司 | 2017-12-22 | — | — | CN | claimed |
| CN-105263933-A | Pyrazino[1,2-a]indole compounds, their preparation and use in medicaments | ESTEVE LABOR DR | 2016-01-20 | — | — | CN | claimed |
| CN-105263933-B | A kind of simultaneously [1,2 a] benzazolyl compounds and preparation method thereof and the application in medicine of pyrazine | 埃斯蒂维实验室股份有限公司 | 2017-12-22 | — | — | CN | disclosed |
| CN-105263933-A | Pyrazino[1,2-a]indole compounds, their preparation and use in medicaments | ESTEVE LABOR DR | 2016-01-20 | — | — | CN | disclosed |