Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC11 | Q96DB2 | 6/20 | 0.56 |
| ▸ | MMP1 | P03956 | 4/20 | 0.48 |
| ▸ | MMP2 | P08253 | 4/20 | 0.48 |
| ▸ | MMP9 | P14780 | 4/20 | 0.48 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.48 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.48 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.45 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.45 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28638168 | 0.81 | HDAC11 (0.49) | HDAC11PSMB8PSMB9PSMB5ALDH1A1 | |
| SCHEMBL28636096 | 0.81 | HDAC11 (0.49) | HDAC11PSMB8PSMB9PSMB5ALDH1A1 | |
| SCHEMBL28261805 | 0.81 | HDAC11 (0.49) | HDAC11PSMB8PSMB9PSMB5ALDH1A1 | |
| SCHEMBL28053627 | 0.79 | MAPT (0.43) | HDAC11PSMB8PSMB9PSMB5HDAC3 | |
| SCHEMBL28261797 | 0.77 | HDAC11 (0.45) | HDAC11PSMB8PSMB9PSMB5ALDH1A1 | |
| SCHEMBL28623304 | 0.77 | HDAC11 (0.45) | HDAC11PSMB8PSMB9PSMB5ALDH1A1 | |
| SCHEMBL28645122 | 0.77 | HDAC11 (0.45) | HDAC11PSMB8PSMB9PSMB5ALDH1A1 | |
| SCHEMBL28053637 | 0.77 | PSMB8 (0.46) | HDAC11PSMB8PSMB9PSMB5HDAC3 | |
| SCHEMBL28826249 | 0.76 | MAPT (0.44) | HDAC11HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL28053635 | 0.75 | MMP1 (0.46) | HDAC11MMP1MMP2MMP9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105272928-A | Alkenyl amide triazole compound and synthetic method thereof | UNIV SHAANXI NORMAL | 2016-01-27 | — | — | CN | disclosed |